
Research Interests
Basic, clinical, and translational research; immunology and immunotherapy; lymphoma; leukemia; liquid and solid tumors; human natural killer (NK) cells; chimeric antigen receptor (CAR) NK cells; proprietary retroviral transduction of human NK cells; genesis of CAR NK cells from peripheral blood, umbilical cord blood, and induced pluripotent stem cells (iPSCs).
Current Affiliations
Professor, Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center and Beckman Research Institute, Duarte, California.
Previous Positions
President and Deana and Steve Campbell physician-in-chief distinguished chair (2018-2023), City of Hope National Medical Center, Duarte, California; chief executive officer (2007-2018) and deputy director (2003-2007), the James Cancer Hospital and Solove Research Institute (2007-2018); vice president, health sciences, Cancer Programs (2003-2018); and director, Division of Hematology and Oncology, Department of Internal Medicine (2000-2007), the Ohio State University, Columbus, Ohio; director (2003-2018); the John L. Marakas Nationwide Insurance Enterprise Foundation chair in cancer research (1997-2017); professor, Department of Internal Medicine (1997-2017); professor, Department of Cancer Biology and Genetics (1997-2017); and associate director, clinical research (1997-2003), the Ohio State University Comprehensive Cancer Center, Columbus, Ohio; co-director, Division of Hematology and Oncology, Department of Internal Medicine (1997-2000), the Ohio State University School of Medicine and Public Health, Columbus, Ohio; professor (1997), associate professor (with tenure) (1994-1997), and assistant professor (1990-1994), Department of Medicine, Roswell Park Cancer Institute and State University of New York at Buffalo School of Medicine, Buffalo, New York; instructor, Department of Medicine, Dana-Farber Cancer Institute, Harvard Medical School (1989-1990), Boston, Massachusetts.
Education
BA, in absentia humanities and health sciences, State University of New York/Buffalo, Buffalo, New York (1997); MS, physiology, Stanford University, Stanford, California (1982); MD, Stanford University School of Medicine, Stanford, California (1983).
Postdoctoral Training
Clinical fellow, medicine (1983-1989); intern (1983-1984) and resident (1984-1986), internal medicine, Brigham and Women’s Hospital; and fellow, medical oncology and tumor immunology, Dana-Farber Cancer Institute (1986-1989), Harvard Medical School, Boston, Massachusetts.
Selected AACR Service, Honors, and Awards
Cochair, AACR Oncology Industry Partnering Event (2024-present); chair, Fellows of the AACR Academy Nomination and Election Oversight Subcommittee (2023-present); scientific editor, AACR Journal, Blood Cancer Discovery (2023-present); treasurer-elect (2022-present); ex officio member, Finance and Audit Committee (2022-present); ex officio member, Executive Committee (2022-present); member, Oncology Development Fund Investment Advisory Committee (2021-present); member, Eliminating Racial Inequities in Cancer Research Task Force (2021-2022); chair, Bylaws Committee (2020-2022); member, Nominating Committee (2020-2022); cochair (2020-2021) and member (2019-2020), Satellite Educational Symposia Committee; member, Finance and Audit Committee (2019-2022); member, AACR Hematologic Malignancies Task Force (2018-2020); elected Fellow, Fellows of the AACR Academy (2018); member, Fellows of the AACR Academy Steering Committee (2018-2021); chair (2018-2019, 2023-2024) and member (2014-2015), AACR Margaret Foti Award for Leadership and Extraordinary Achievements in Cancer Research; chair, AACR Cancer Progress Report Steering Committee (2017); president, AACR (2017-2018); member, Executive Committee (2016-2019); member, Council of Scientific Advisors (2014); member, Board of Directors (2013-2016); member, Clinical and Translational Cancer Research Committee (2012-2015); member, Landon Foundation-AACR INNOVATOR Award for Cancer Prevention Scientific Review Committee (2011); senior editor, AACR Journal, Cancer Epidemiology, Biomarkers & Prevention (2010-2012); member, Cancer Immunology Working Group Steering Committee (2008-2011); chair, Publications Committee (2003-2016); chair, Annual Meeting Program Committee (2008-2009); conference cochair, AACR-NCI-EORTC Conference, “Molecular Targets and Cancer Therapeutics,” Frankfurt, Germany (2002); member, Science Policy and Government Affairs Committee (2001-2004, 2012-2015, 2020-2023).
Selected Non-AACR Service, Honors, and Awards
Recipient, Basic Science Mentor Award, American Society of Hematology (2022); honoree, Tullman Lecture in Hematology, Yale Cancer Center (2019); keynote speaker, Californa Cancer Registrars Association Annual Education Meeting, “Precision Medicine” (2019); recipient, the Ohio State University Human Cancer Genetics Award (2018); elected member, National Academy of Medicine (2018); recipient, J. E. Wallace Sterling Lifetime Achievement Award in Medicine, Stanford University School of Medicine (2018); recipient, Simon M. Shubitz Lecturer and Award, University of Chicago CCC (2018); recipient, Outstanding Investigator Award, National Cancer Institute (2016); member, Editorial Board, Cancer Today (2016-present); recipient, Diversity and Inclusion Shining Star for Faculty Mentorship, the Ohio State University College of Medicine (2011); elected councilor, Board of Directors, American Society of Hematology (2011-2015); recipient, NCI Director’s Service Award (2012); recipient, NCI MERIT Award (2010); recipient, NCI Eminent Lecture Award (2010); honoree, Mario Baldini Visiting Professor, Harvard Medical School-Beth Israel Hospital (2009); member, Board of Directors, Pelotonia (2008-2017); elected member, Alpha Omega Alpha Honor Medical Society (2008); member, Board of Scientific Advisors, NCI (2008-2012); recipient, John Wayne Clinical Research Award, Society of Surgical Oncologists (2008); member, Board of Directors, Association of American Cancer Institutes (2005-2011); recipient, American Cancer Society John P. Minton Hero of Hope Research Champion Medal of Honor Award (2004); elected member, Association of American Physicians (2004); fellow, American Association for the Advancement of Science (2003); honoree, Distinguished University Scholar, the Ohio State University (2002); vice chair, Scientific Advisory Board, Cure for Lymphoma Foundation (2000-2004); recipient, Emil J. Freireich Award in Clinical Cancer Research, MD Anderson Cancer Center (1999); elected member, American Society for Clinical Investigation (1998); fellow, American College of Physicians (1998).