Research Interests
Cancer biology, genetics, and diagnostics; redisposition to hereditary nonpolyposis colon cancer (HNPCC); novel mutations in chromatin remodeling genes in human cancers; development of clinical applications in early detection, and monitoring of cancer using liquid biopsy; non-invasive detection of multiple types of cancer (CancerSEEK).
Current Affiliations
Professor, oncology, human genetics and pathology; and director, translational genetics, Ludwig Center at Johns Hopkins, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.
Previous Positions
Assistant professor, pathology, Presbyterian Hospital (1997-2000); assistant professor (1999-2000) and adjunct assistant professor (2000-2006), Institute for Cancer Genetics, Columbia University, New York, New York; visiting associate professor, Johns Hopkins Oncology Center (2005-2006), Baltimore, Maryland; associate professor of oncology, Johns Hopkins School of Medicine (2006-2012), Baltimore, Maryland.
Education
BS, biology, Aristotle University of Thessaloniki, Thessaloniki, Greece (1985); MS, biology, University of Houston, Houston, Texas (1988); PhD, biomedical sciences, University of Texas Health Science Center at Houston, Houston, Texas (1992).
Postdoctoral Training
Fogerty fellowship, National Institutes on Aging, Gerontology Research Center, NIH (1992-1993), Baltimore, Maryland; postdoctoral fellow, oncology (1993-1996); and research associate (1996-1997), Johns Hopkins University School of Medicine, Baltimore, Maryland.
Selected AACR Service, Honors, and Awards
Co-editor-in-chief, AACR Journal, Cancer Prevention Research (2024-present); member, Editorial Board (2023-present) and scientific editor (2020-2023), AACR Journal, Cancer Discovery; member, AACR Exploratory IND/Phase 0 Clinical Trials Task Force (2021-present); member, AACR Cancer Progress Report Steering Committee (2019-2020); member, AACR Team Science Award Committee (2018-2020); member, Pancreatic Cancer Action Network-AACR Career Development Awards Scientific Review Committee (2015-2017); recipient, AACR Team Science Award (2013, 2014, 2017); co-chairperson, AACR Special Conference in Cancer Research: Metabolism and Cancer (2011).
Selected Non-AACR Service, Honors, and Awards
Co-founder and member, Board of Directors, Haystack Oncology Inc. (2021-2023); recipient, The Dr. George N Papanicolau Award, The Hellenic Medical Society (2019); cofounder and member, Board of Directors, Thrive Inc (2019-2020); member, Scientific Advisory Board, Science Translational Medicine (2018-present); recipient, Director’s Teaching Award in Laboratory-Based Science, Johns Hopkins (2017); lecturer, the Annual Lauren T. Erb Lecture, Neuroendocrine Tumor Research Foundation (2017); president and cofounder, PapGene Inc. (2014-2019); consultant, Sysmex-Inostics (2014-2017); recipient, Commonwealth Award (2011); recipient, Carrying for Carcinoid Foundation Award (2009, 2011); recipient, SPORE Career Award (2007); consultant, Gerson Lehrman Group Councils (2007-2008); consultant, Exact Sciences Inc. (2006-2007, 2021-present); consultant, Helicos Biosciences, Inc. (2004-2005); consultant (2004-2005), vice president (2002-2004), and chief scientific officer (2000-2004), GMP Genetics; recipient, V Foundation Award; recipient, CapCURE Young Investigator Award.