American Cancer Society Professor
Molecular and Cell Biology Laboratory
Renato Dulbecco Chair
Salk Institute for Biological Studies
La Jolla, California
For his seminal discovery of tyrosine kinases and tyrosine phosphorylation of proteins that illuminated fundamental processes of cellular signaling and enabled the development of cancer therapeutics targeting these kinases. His basic biomedical research targeting tyrosine kinases has successfully been translated to over 60 tyrosine kinase inhibitors, clinically approved to treat and manage a multitude of cancers and other diseases
The AACR Award for Lifetime Achievement in Cancer Research was established in 2004 to honor individuals who have made significant fundamental contributions to cancer research, either through a single scientific discovery or a collective body of work. These contributions, whether they have been in research, leadership, or mentorship, must have had a lasting impact on the cancer field and must have demonstrated a lifetime commitment to progress against cancer.
Dr. Hunter is being honored for the discovery of protein tyrosine phosphorylation as a common cellular mechanism capable of contributing to cellular growth and proliferation and, in some cases, the development of cancer. This discovery has since led to the development of over 50 tyrosine and serine kinase inhibitors and has firmly established a new class of targeted cancer therapies. To learn more, please visit the press release.