Tunde Marcus Smith, BS

Tunde Marcus Smith, BS

Graduate Student
Meharry Medical College
Nashville, Tennessee

Abstract 3266. The KDM5 inhibitor PBIT reduces proliferation of castration-resistant prostate cancers via the induction of senescence.

What are your long-term career objectives?

My current research interest involves identifying therapeutic strategies for advanced prostate cancers. I am specifically interested in defining the role of the histone lysine demethylase family, KDM5, in castration resistant prostate cancer progression as well as determining how compounds that inhibit the KDM5 family influence prostate cancer cell migration and invasion, cancer cell viability and proliferation, and cell cycle progression. My career ambition is to become an independent research investigator in the biotechnology industry who studies the role of epigenetics in cancer drug resistance. I also have ambitions to work as a medical science liaison, using my interpersonal skills and passion for simplifying complex ideas and systems to ease the translation of cutting-edge research. 

Please share information about how the COVID-19 pandemic has impacted your research over the last two years. 

In the first few months of the COVID-19 pandemic, my research was impacted tremendously as most labs were shut down for students due to the Meharry Medical College COVID-19 guidelines. However, as the pandemic progresses I have been able to maintain my experiments with the new guidelines such as vaccination requirements and weekly testing in place.