Cancer Research at a Crossroads: AACR Efforts to Defend Science and Protect Patients

From the Administration’s abrupt and indiscriminate dismissals of dedicated public servants at the National Institutes of Health (NIH), to their proposed major cuts to leading research institutions and cancer centers across the United States, to their more recent efforts to slash the NIH budget by nearly 40 percent, the cancer research community has been under attack. The AACR has led efforts to defend the NIH and sustain the remarkable progress that has been made against cancer over the past 50 years as a result of federally-funded cancer science and medicine.

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February 2025: Response to Executive Orders

On February 18, the AACR issued a Statement and Call to Action Regarding the Administration’s Actions Affecting NIH and the American People

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April 2025: Cancer Research Saves Lives

During the Opening Ceremony at the AACR Annual Meeting 2025, 2024-2025 AACR President Patricia M. LoRusso led attendees in a united demonstration of support for federally funded cancer research.

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April 2025: Launch of AACR Trailblazer Grant Program

In response to the disruptions in federal cancer funding, the AACR launches its largest-ever grant program—15 grants of $1 million each to support early-stage and mid-career investigators.

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April 2025: Sustaining Progress

During the AACR Annual Meeting 2025, the AACR hosted a panel discussion to discuss ways to safeguard progress while facing the Administration’s threats to the cancer research enterprise. The panel featured former NCI Director Kimryn Rathmell and former NIH Director Monica M. Bertagnolli.

Learn More on the AACR Blog
April 2025: “We Stand at the Edge of Discovery…”

“…and the brink of losing it.”
2024-2025 AACR President Patricia M. LoRusso highlighted the remarkable progress made against cancer and the consequences of cutting funding for cancer research during a special panel discussion at the AACR Annual Meeting.

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May 2025: Response to Proposed FY2026 Budget

In a statement on May 6, the AACR called on Congress to summarily reject the President’s FY2026 budget proposal for NIH, which would result in a nearly 40% cut to the Institute’s budget for lifesaving research.

Read the Statement
May 2025: AACR-AACI Hill Day

On May 21–22, the AACR partnered with the Association of American Cancer Institutes for their annual Joint Hill Day. Cancer center directors and AACR members visited their Congressional representatives to highlight the value of bipartisan investment in NIH and NCI.
View photos from the Hill Day.

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May 2025: One Mission. One Voice.

During National Cancer Research Month, the AACR brought together cancer centers, institutions, researchers, physicians, patients, survivors, and advocates to highlight the importance and impact of cancer research.

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The Impact of disruptions to the NIH

Disruptions to the NIH affect every member of the cancer research community, including early-career scientists and especially the patients who rely on federally-funded advances to extend their lives.

“These Are Not Just Missed Opportunities…”

“…they are structural failures that force promising researchers out of science.” 2024-2025 AACR President Patricia M. LoRusso describes the impact of funding disruptions on the next generation of cancer researchers.

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“We Have Gotten So Much Progress…”

“…and we need to keep this going.” Michael Methner is an 11-year-old cancer survivor featured in the AACR Cancer Progress Report. At a briefing in Washington to present the report to Congress, he took the microphone and asked legislators to continue their longstanding bipartisan support for medical research that benefits children like him.

Read Michael’s Story
“When Science Is Silenced, Patients Pay the Price.”

2024-2025 AACR President Patricia M. LoRusso notes that disruptions to federally funded biomedical research could force the delay or cancellation of clinical trials of experimental therapeutics for a wide range of diseases, including cancer.

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NIH Funding Sustains the Pace of Innovation

Vicki Jones has lived with her multiple myeloma diagnosis for 20 years because progress in cancer research has outpaced progression of her disease. Upheavals at NIH threaten to disrupt the delivery of new treatments that patients like Vicki desperately need to extend their lives.

Read Vicki’s Story