Elironrasib May Overcome Resistance to Prior KRAS G12C Inhibition in Non-small Cell Lung Cancer
The small molecule KRAS inhibitor elironrasib targets the active GTP-bound form of KRAS G12C and led to encouraging responses...
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New Targeted Therapy Shows Promise for Patients With Advanced Bladder Cancer
BOSTON – FX-909, a first-in-class investigational oral small molecule inhibitor of peroxisome proliferator-activated receptor gamma (PPARG), showed early signs...
Zenocutuzumab Shows Clinical Benefit in Rare Bile Duct Cancer
BOSTON – Zenocutuzumab (Bizengri), a bispecific antibody that targets human epidermal growth factor receptor 2 (HER2) and HER3, led...
Investigational Antibody-drug Conjugate Shows Clinical Benefit Against Previously Treated Small Cell Lung Cancer
Patients with brain metastasis experienced responses in the phase I clinical trial BOSTON – Zocilurtatug pelitecan (zoci), also known as ZL-1310, an...
AACR Congratulates Members Elected to the National Academy of Medicine
PHILADELPHIA – The American Association for Cancer Research (AACR) extends its sincerest congratulations to the nine AACR members who...
New Combination Therapy Shows Promise for Aggressive Lymphoma Resistant to Immunotherapy
Epigenetic therapy boosted immunotherapy response in refractory natural killer/T-cell lymphoma by turning cold tumors hot PHILADELPHIA – Combining an...
Armando E. Giuliano, MD, Honored With 2025 William L. McGuire Memorial Lecture Award
SAN ANTONIO – Armando E. Giuliano, MD, will receive the William L. McGuire Memorial Lecture Award during the 2025...
Medicaid Expansion Linked to Improved Long-term Survival in Cancer Patients
Certain cancer patients in U.S. states that expanded Medicaid experienced increased survival, especially in rural and high-poverty regions PHILADELPHIA...
Dennis Lo, DM, DPhil, Honored With 2026 AACR-Irving Weinstein Foundation Distinguished Lectureship
SAN DIEGO – The American Association for Cancer Research (AACR) will award the 22nd AACR-Irving Weinstein Foundation Distinguished Lectureship...
A Polygenic Risk Score May Predict Future Breast Cancer in Patients With Early-stage Diagnoses
Patients diagnosed with abnormal breast cells were more likely to receive a later diagnosis of breast cancer if their...