AACR Annual Meeting 2025 Press Program

The American Association for Cancer Research (AACR) hosted its 116th Annual Meeting from April 25-30, 2025, at McCormick Place Convention Center in Chicago.

To help reporters plan coverage of the meeting, the AACR public relations team prepared the following press program.

Press Conference 1

AACR Annual Meeting Clinical Trials Committee Cochair Ryan B. Corcoran, MD, PhD, Mass General Cancer Center, moderated the first press conference on Sunday, April 27.

The following studies were presented:

Oral Investigational Agent Zoldonrasib Elicits Objective Responses in Patients With KRAS G12D-mutated Lung Cancer

• Presented by Kathryn C. Arbour, MD, Memorial Sloan Kettering Cancer Center

Adding Perioperative Pembrolizumab to Standard of Care Improves Outcomes in Patients With Newly Diagnosed Head and Neck Cancer

• Presented by Ravindra Uppaluri, MD, PhD, Dana-Farber Brigham Cancer Center and Harvard Medical School

Neoadjuvant PD-1 Blockade in Early-stage Mismatch Repair-deficient Cancers Can Eliminate the Need for Surgery Regardless of Tumor Type

• Presented by Andrea Cercek, MD, Memorial Sloan Kettering Cancer Center

View Press Conference 1

pRESS cONFERENCE 2

Oral HER2-targeted Therapy Zongertinib Demonstrates Clinical Benefit in Advanced HER2-mutated Lung Cancer

• Presented by John V. Heymach, MD, PhD, University of Texas MD Anderson Cancer Center

AI-driven Analysis of Digital Pathology Images May Improve Pediatric Sarcoma Subtyping

• Presented by Adam Thiesen, UConn Health and The Jackson Laboratory

A Liquid Biopsy-based Assay Could Detect Recurrence Prior to Imaging in Patients With Resectable Colorectal Cancer

• Presented by Emma Titmuss, MSc, BC Cancer

View press conference 2

Press Conference 3

Cancer-related Fatigue and Depression May Lead to Decrease in Recreational Physical Activities and Quality of Life in Survivors

• Presented by Simo Du, MD, MHS, NYC Health + Hospitals/Jacobi and Albert Einstein College of Medicine

Breast Cancer Mortality in Women Ages 20-49 Significantly Dropped Between 2010 and 2020

• Presented by Adetunji Toriola, MD, PhD, MPH, Siteman Cancer Center at Washington University School of Medicine

Patient Outcomes May Improve With Tailored Treatment Guided by Tissue Plus Liquid Biopsies vs. Individually 

• Presented by  Paolo Marchetti, MD, Istituto Dermopatico dell’Immacolata (IDI-IRCCS) in Rome

View press conference 3

Additional Press releases

Adjuvant PD-1 Blockade for Mismatch Repair-deficient Solid Cancers Directed by ctDNA Status Delivers Clinical Benefit

• Presented by Yelena Y. Janjigian, MD, Memorial Sloan Kettering Cancer Center

AI-driven Biomarker Model May Improve Detection of Cancer Cachexia

• Presented by Sabeen Ahmed, University of South Florida and Moffitt Cancer Center

Pretrained Machine Learning Models May Help Accurately Diagnose Nonmelanoma Skin Cancer in Resource-limited Settings

•  Steven Song, Pritzker School of Medicine and the University of Chicago

Off-the-shelf CAR Natural Killer Cell Therapy Elicits Complete Remission of Relapsed or Refractory Blood Cancers

•  Presented by Stephen Strickland, Jr., MD, MSCI, Sarah Cannon Research Institute

A Topical BRAF-inhibiting Gel May Mitigate Acneiform Rash in Patients Receiving EGFR-targeted Therapy for Colorectal Cancer

• Presented by Anisha B. Patel, MD, The University of Texas MD Anderson Cancer Center

Single-cell RNA Sequencing Provides Comprehensive Map of Acute Myeloid Leukemia Cell States

• Presented by Andy Zeng, PhD, an MD/PhD student at the University of Toronto