The Breast Cancer Research Foundation-AACR Career Development Awards for Translational Breast Cancer Research support innovative breast cancer-focused research. 2018 recipient Camila dos Santos, PhD, shared how her career development award made an impact on her research and career.
Research Funding Impact
Since 1993, the AACR has awarded more than $480 million in grants to fund meritorious research projects across the spectrum of cancer science, including basic, translational, and clinical research. See how the AACR grants program has contributed to the AACR's mission.
AACR-AstraZeneca Immuno-Oncology Fellow Uncovers a Role for Tissue-Resident Macrophages in Early Lung Cancer Development
2020 AACR-AstraZeneca Immuno-Oncology Fellow, Maria Casanova-Acebes, PhD, now current head of the Cancer Immunity Group at the Spanish National Cancer Research Centre (CNIO), reported in Nature their findings on how tissue-resident macrophages may influence lung cancer development.
The AACR-Bayer START grant gives early career investigators the unique opportunity to gain experience not only in academic but also in industry settings. Mark Labrecque, PhD, speaks on the impact of this grant on his career and research.
AACR-Incyte Immuno-Oncology Fellow Shows Therapeutic Potential of Targeting TCR Signaling Phosphatase PTPN22
Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been primarily studied in the context of autoimmune diseases. 2019 AACR-InCyte Immuno-oncology Fellow Won Jin Ho, MD, showed how PTPN22 inhibition retards tumor growth in a T-cell- and macrophage-dependent manner.
Collaborations for Smoking Cessation: The 2019 AACR-Johnson & Johnson Lung Cancer Innovation Science Grants
In recognition of the need to advance the science of lung cancer prevention and interception, the 2019 AACR-J&J Lung Cancer Innovation Science Grants program awarded grants to two multi-institutional teams whose multifaceted projects seek to understand how an individual’s genetics may affect smoking-related behaviors and quit attempts, as well as to develop clinically actionable smoking cessation strategies that will improve patient outcomes.
More than half of melanomas contain extra copies of the sirtuin 5 gene. Two AACR-Bayer Innovation and Discovery grant recipients and an AACR NextGen Grant recipient, along with their colleagues, demonstrated that sirtuin 5 is required for melanoma cell proliferation and survival.
AACR grantee Yi Fan, PhD, shared how flexible funding from an AACR Judah Folkman Career Development Award allowed him to explore an unconventional angle of anti-vascular therapy; namely, targeting genetic endothelial transformation, to fight the deadliest of brain cancers.
The partnership of the AACR with QuadW reflects the commitment of both organizations to make a difference in the lives of sarcoma patients by supporting the next generation of cancer researchers who are focused on sarcoma research.