AI as a Clinical Copilot: Advancing Precision Oncology Through Spatial Biology
As highlighted in AACR’s Cancer Catalyst blog, 2024 AACR Innovation and Discovery Grant recipient Tae Hyun Hwang, PhD, is helping define how artificial intelligence can function as a clinical copilot in cancer care. Through his AACR-supported project, Dr. Hwang has developed AI-driven tools that integrate digital pathology with spatial molecular profiling to better understand why some tumors resist immunotherapy. His work reveals how tumor architecture and stromal “barriers” can prevent immune cells from reaching cancer cells, contributing to treatment failure. By pairing AI with spatial transcriptomics and in situ imaging, his team has begun to map these interactions at high resolution, uncovering new biomarkers and therapeutic targets to guide more precise, personalized treatment strategies.
