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Innovators in Discovery

Home Patients, Caregivers, and Advocates Innovators

Cancer researchers, physician-scientists, and others are driving progress against cancer with discoveries that are advancing prevention and transforming care.

Charles L. Sawyers, MD, Fellow of the AACR Academy

Charles L. Sawyers, MD, Fellow of the AACR Academy

As a physician scientist and leader in the development of targeted therapies for cancer, Dr. Sawyers investigates the signaling pathways that drive the growth and drug resistance of cancer cells.

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Ronald M. Evans, PhD, Fellows of the AACR Academy

Ronald M. Evans, PhD, Fellows of the AACR Academy

A renowned authority on hormones and their role in disease, Dr. Evans has conducted research that has led to the discovery of nearly 50 nuclear hormone receptors.

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Susan B. Horwitz, PHD, Fellow of the AACR Academy

Susan B. Horwitz, PHD, Fellow of the AACR Academy

Dr. Horwitz's contributions to the field encompass agents that have served as prototypes for some of the most important drugs currently in clinical use. Her most seminal contribution has been in the development of Taxol®, a drug isolated from the yew plant, Taxus brevifolia.

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Judy E. Garber, MD, MPH, Fellow of the AACR Academy

Judy E. Garber, MD, MPH, Fellow of the AACR Academy

An internationally recognized leader in clinical and translational research on breast cancer, Dr. Garber developed one of the first cancer risk and prevention clinics where programs are now being expanded to several types of cancer.

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Distinguished Scientist Earns International Recognition

Distinguished Scientist Earns International Recognition

Fellow of the AACR Academy John E. Dick, PhD, earns the 2020 Pezcoller Foundation-AACR International Award for Extraordinary Achievement in Cancer Research.

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William G. Kaelin, Jr., MD: Fellow of the AACR Academy

William G. Kaelin, Jr., MD: Fellow of the AACR Academy

A leader in the study of how mutations affecting tumor-suppressor genes cause cancer, Dr. Kaelin's research has had major clinical implications for several forms of cancer, particularly kidney cancer. Dr. Kaelin, Sir Peter J. Ratcliffe, MD, FRS, and Gregg L. Semenza, MD, PhD, were awarded the 2019 Nobel Prize in Physiology or Medicine.

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Aiming for Equal Access to Precision Cancer Genomics

Aiming for Equal Access to Precision Cancer Genomics

Elaine R. Mardis, PhD, spends a lot of her time studying molecules at the Institute for Genomic Medicine at Nationwide Children’s Hospital in Columbus, Ohio. What she sees is invisible to the naked eye, but her vision for what clinicians can do with the information they find in the genes of a cancer cell is clear.

Read more in Leading Discoveries magazine
Closing Disparities Through Genetic Testing

Closing Disparities Through Genetic Testing

Dr. Olufunmilayo Olopade, a physician-scientist and director of the Center for Clinical Cancer Genetics at the University of Chicago Medical Center seeks widespread use of testing to encourage prevention and early detection of deadly cancers.

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Sustaining Researchers at ‘Critical Transition Points’

Sustaining Researchers at ‘Critical Transition Points’

W. Kimryn Rathmell, MD, PhD, director of the Division of Hematology and Oncology at Vanderbilt University Medical Center in Nashville, has twice been awarded grants by the American Association for Cancer Research (AACR). “The AACR does a great job of identifying high-risk, high-reward research,” Dr. Rathmell said.

Read more in Leading Discoveries magazine
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