In This Section

AACR-MPM Oncology Charitable Foundation Transformative Cancer Research Grants

Grant Amount $400,000 USD
Grant Term2 Years
Start of Grant TermDecember 1, 2022
Letter of Intent DeadlineJune 16, 2022 1:00 PM (ET)
Application DeadlineOctober 11, 2022 1:00 PM (ET)
Decision DateNovember 2022
Additional InformationAdditional details regarding this grant program can be found in the Program Guidelines and Application Instructions. Final determinations of eligibility will not be completed until the AACR is in receipt of the submitted application.

The AACR-MPM Oncology Charitable Foundation Transformative Cancer Research Grants represents a joint effort to stimulate “high-risk, high-reward” research from early- to mid-career investigators. This grant mechanism is intended to promote and support creative, paradigm-shifting cancer research that might not be funded through conventional channels. It is expected that these grants will catalyze significant scientific discoveries that will advance our understanding of cancer and have a potentially transformative impact on future clinical practice.

The grants provide $400,000 over a two-year period for expenses related to the research project, which may include salary and benefits of the grant recipient and any collaborators (grant recipient/collaborator salaries limited to 25% of the total grant), postdoctoral or clinical research fellows, graduate students (including tuition costs), and research assistants, research/laboratory supplies, equipment, travel applicable to the research project, publication charges for manuscripts that pertain directly to the funded project, and other research expenses. Indirect costs are not allowable expenses.

Program Guidelines

Download Program Guidelines and Application Instructions here.

Research Project Criteria

The proposed research must represent a highly innovative approach to a major problem or challenge in cancer research. The funded projects are expected to catalyze important advances in cancer research, and should have a potentially transformative impact on future clinical practice. The research can be in any area of basic, translational, or clinical research.

Eligibility Criteria

Applicants must have a doctoral degree (including PhD, MD, MD/PhD, or equivalent) in a related field and not currently be a candidate for a further doctoral degree. At the start of the grant term on December 1, 2022, applicants must:

  • Hold an appointment at the rank of assistant or associate professor.
    • If eligibility is based on a future position, the position must be confirmed at the time of submission, and CANNOT be contingent upon receiving this grant.
    • If the future position is at a different institution than the applicant’s current institution, the applicant must contact the AACR’s Scientific Review and Grants Administration Department (the AACR’s SRGA) at [email protected] before submitting their Letter of Intent for information on additional verification materials/signatures that may be required.
  • Work at an academic, medical, or research institution anywhere in the world.
Citizenship Requirements

There are no citizenship or geographic requirements. However, by submitting a Letter of Intent for this grant, an applicant applying from an institution located in a country in which they are not a citizen or a permanent resident assures that their visa status will provide sufficient time to complete the project and grant term at the institution from which they applied.

AACR Membership Requirements

Applicants must be AACR Active members. Nonmembers interested in this grant opportunity must submit a satisfactory application for AACR Active membership by the application deadline. Nonmembers can apply for membership online. Please review the Membership Categories for the category that best fits your qualifications. Members can renew their membership through myAACR to bring their membership current. You will need your logon (email address) and password to access the member portal. If you required assistance logging in, please contact [email protected]Lapsed members must be members in good standing by the application deadline and should contact the Membership Department at [email protected] for assistance.

Application Instructions

The AACR requires applicants to complete an online Letter of Intent submission by 1:00 p.m. U.S. Eastern Time on Thursday, June 16, 2022, using the ProposalCentral website at

Competitive Letter of Intent Program Guidelines and Application Instructions are available for download here.