Daniel F. Liefwalker, PhD

Daniel F. Liefwalker, PhD

Research Assistant Professor
Oregon Health and Science University
Portland, Oregon

Abstract 825. Evasion of apoptosis in MYC dependent T-ALL through epigenetic control.

What are your long-term career objectives?

My long-term research vision is to bring new knowledge by developing a research program investigating: 1) How oncogenic MYC escapes apoptotic feedback in cancer; 2) Discover how oncogenes avert apoptosis through metabolic reprogramming and epigenetics in oncogenic settings; and 3) Test potential therapeutic strategies that inhibit oncogenic editing of apoptotic responses. Additionally, I am motivated to provide mentorship to young investigators, especially those from traditionally underrepresented and marginalized backgrounds.

Please share information about how the COVID-19 pandemic has impacted your research over the last two years.

I have experienced substantial restraints on my career trajectory due to the unanticipated outbreak of SARS-CoV-2. The severe impacts on my career goals and research occurred at a critical time during my four-year K01 award, resulting in a delayed transition to tenure-track faculty, missed career development opportunities, and postponed potential collaborations. Additionally, the pandemic created personal circumstances which acutely inhibited my ability to conduct research, prevented interactions with mentors and departmental faculty, and isolated my research program. Despite these obstacles, I have continued to be productive.