Dr. Jaffee is the first recipient of the Dana and Albert “Cubby” Broccoli professorship in oncology at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, and also holds a professorship in pathology at the Johns Hopkins University School of Medicine. Since 2015, she has been deputy director of the Kimmel Cancer Center. She is also the co-director of the Skip Viragh Center for Pancreas Cancer Clinical Research and Patient Care. Her research is focused on the development of novel vaccine approaches that overcome immune tolerance to cancers. She has completed multiple studies testing an allogeneic tumor vaccine in patients with pancreatic cancer who were eligible for complete surgical resection of their tumors, but whose cancers are still expected to recur at rates as high as 80% one year following surgery.