Gastric Cancer Awareness Month
Stomach cancer, also known as gastric cancer, is a disease in which cancer cells form in the lining of the stomach. The wall of the stomach is made up of three layers of tissue: the mucosal layer, the muscularis layer, and the serosal layer. Stomach cancer begins in the cells lining the mucosal layer and spreads through the outer layers as it grows.
Most stomach cancers – about 90 percent – are adenocarcinomas, cancers that form in mucus-secreting glands. About 5 percent of them are lymphomas, cancers that form in the immune system. Additionally, some stomach tumors are of the carcinoid type, a slow-growing type of neuroendocrine cancers.
Stromal tumors of the stomach begin in supporting connective tissue and are treated differently from gastric cancer.
An estimated 27,510 new cases of stomach cancer will be diagnosed in the United States and 11,140 people are expected to die from the disease in 2019, according to the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute (NCI).
Men are more commonly diagnosed with stomach cancer than women. Moreover, stomach cancer is less frequent among non-Hispanic whites than people of other races and ethnicities. Risk factors include smoking, age, diet, and long-term stomach inflammation, such as infection with Helicobacter pylori bacteria, according to the NCI.
Since 2014, the American Association for Cancer Research (AACR) and Debbie’s Dream Foundation: Curing Stomach Cancer have together offered research grants in the field of gastric cancer. The Debbie’s Dream Foundation-AACR Gastric Cancer Fellowship, in Memory of Candice Netzer, and the Debbie’s Dream Foundation-AACR Career Development Award for Gastric Cancer Research represent a joint effort to encourage and support postdoctoral or clinical research fellows to conduct gastric cancer research.
The 2019 grants were awarded to: Ankur Nagaraja, MD, PhD, of the Dana-Farber Cancer Institute; Katsumi Yamaguchi, PhD, of Johns Hopkins University; and Youn-Sang Jung, PhD, of The University of Texas MD Anderson Cancer Center.
Additionally, the AACR awarded an AACR Scholar-in-Training Award to Jin Young Yoo, Seoul National University (Republic of Korea) for his gastric cancer research.