Paranasal Sinus and Nasal Cavity Cancer

The most common type of paranasal sinus and nasal cavity cancer is squamous cell carcinoma. This type of cancer forms in the thin, flat squamous cells that line the inside of the paranasal sinuses and the nasal cavity. Other types of paranasal sinus and nasal cavity cancer include: melanoma, sarcoma, and midline granulomas.

Risk factors for paranasal sinus and nasal cavity cancer include smoking and human papillomavirus (HPV) infection as well as exposure to certain chemicals or dust during furniture making, sawmill work, woodworking, shoemaking, and flour mill or bakery work.

The majority of tumors of the paranasal sinuses are discovered at advanced stages when cure rates are generally poor. Paranasal sinus and nasal cavity cancer is a type of head and neck cancer.

Paranasal sinus and nasal cavity cancer is a type of head and neck cancer, which includes cancers of the oral cavity, pharynx (throat), larynx (voice box), paranasal sinuses, nasal cavity, and salivary glands. About 71,100 cases of head and neck cancer are expected to be diagnosed in the United States in 2024, and about 16,110 deaths will occur, according to the National Cancer Institute.

Paranasal Sinus and Nasal Cavity Cancer Treatment (Adult) (PDQ®)

Source: National Cancer Institute