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Progress Against Cancer

Home Patients, Caregivers, and Advocates Progress Against Cancer Research Page 12

Recent Progress: Cancer Discoveries

AACR Grantee Identifies Novel Combination Therapy for Epithelial Ovarian Cancer

AACR Grantee Identifies Novel Combination Therapy for Epithelial Ovarian Cancer

Epithelial ovarian cancer is by far the most common ovarian cancer subtype, accounting for 90 percent of ovarian cancers. The complex genetic heterogeneity of this disease makes treatment particularly difficult. While the introduction of PARP inhibitors to treat ovarian cancers has been a major advancement, only the approximately 50 percent of epithelial ovarian cancers that exhibit defective DNA repair via homologous recombination are potentially responsive to PARP inhibition. Moreover, the development of therapeutic resistance remains a challenge.

An Ounce of Prevention: Cervical Cancer Awareness Month

An Ounce of Prevention: Cervical Cancer Awareness Month

Once the leading cause of cancer-related mortality among women, cervical cancer now accounts for less than 1 percent of cancer-related deaths among women in the United States. This dramatic decrease is largely due to the implementation of screening, which can detect precancerous lesions and early-stage cancer, and vaccination, which can prevent the cancer from developing at all.