Postmenopausal Women With Early-stage Breast Cancer and Low Recurrence Score Could Skip Adjuvant Chemotherapy
Adjuvant chemotherapy may yield improved survival outcomes for premenopausal counterparts SAN ANTONIO – After a median follow-up of 5.1...
Study Finds Racial Disparity in Pro-metastatic Tumor Microenvironment Among Women With Residual Breast Cancer After Neoadjuvant Chemotherapy
SAN ANTONIO – Residual tumors from Black patients with estrogen receptor (ER)-positive/HER2-negative primary breast cancer treated with neoadjuvant chemotherapy...
Younger Postmenopausal Patients With Early-stage Breast Cancer May Be Able to Safely Omit Adjuvant Radiotherapy
Results are from a five-year follow-up; long-term study is needed SAN ANTONIO – Almost all postmenopausal patients aged 50-69...
Residual Cancer Burden Can Predict Outcomes for Patients With Any Breast Cancer Type
SAN ANTONIO — A large meta-analysis of breast cancer patients showed that residual cancer burden after neoadjuvant chemotherapy is...
Menopausal Hormone Therapy May Not Pose Breast Cancer Risk for Women With BRCA Mutations
SAN ANTONIO – Using menopausal hormone therapy (MHT) was not associated with an increased risk of breast cancer in...
Exercise Performed During Adjuvant Breast Cancer Treatment May Improve Cardiovascular Function
SAN ANTONIO – Women who underwent a supervised program of cardiovascular exercise during adjuvant breast cancer treatment experienced better...
Disparities in Toxic Heavy Metal Exposures Correlated With Increased Risk of Breast Cancer Among Minority Populations in Chicago
SAN FRANCISCO – Among women in Chicago, African Americans and Hispanics were exposed to higher levels of ambient toxic...
Acupuncture May Help Improve Perceived Breast Cancer-related Cognitive Difficulties Over Usual Care
SAN ANTONIO – Real and sham acupuncture were more effective at improving breast cancer survivors’ perceived cognitive impairment compared...
Breast Cancer Mortality in Women Ages 20-49 Significantly Dropped Between 2010 and 2020
CHICAGO – From 2010 to 2020, breast cancer deaths among women ages 20-49 declined significantly across all breast cancer...
Sentinel Lymph Node Biopsy May Be Safely Omitted in Some Patients With Early-stage Breast Cancer
Omission of sentinel lymph node biopsy did not change five-year recurrence rates SAN ANTONIO – Skipping sentinel lymph node...
Liquid Biopsy Augments MRI for Predicting Response to Neoadjuvant Treatment in Patients With Breast Cancer
PHILADELPHIA – A liquid biopsy test to assess plasma cell-free DNA (cfDNA) integrity could improve the accuracy of magnetic...
PARP Inhibition Shows Long-term Survival Benefits for Patients With High-risk, BRCA-positive Breast Cancer in OlympiA Trial
SAN ANTONIO – Patients with high-risk, BRCA-positive breast cancer who received olaparib (Lynparza) after standard treatment continued to have...
Adding Tucatinib to First-line Maintenance Therapy Delayed Disease Progression in HER2-positive Metastatic Breast Cancer in HER2CLIMB-05 Trial
Benefit was seen across all subgroups, including in patients with brain metastasis SAN ANTONIO – Adding tucatinib (Tukysa) to...
Young Women with Breast Cancer May Face Financial Hardship After Diagnosis
Cancer experience affects work performance, career decisions, and personal debt PHILADELPHIA – Young women with breast cancer experienced substantial...
Neoadjuvant Trastuzumab Deruxtecan Shows Clinical Activity in Patients With HER2-low Breast Cancer
SAN ANTONIO – Patients with localized, hormone receptor-positive, HER2-low breast cancer treated with trastuzumab deruxtecan (T-DXd, Enhertu) in the...
Most Patients With Intermediate-risk Breast Cancer May Safely Avoid Chest Wall Irradiation After Mastectomy
SAN ANTONIO – Patients with intermediate-risk breast cancer had similar rates of 10-year overall survival whether or not they...
Black Women are More Likely to Develop Lymphedema Following Breast Cancer Treatment than White Women
SAN ANTONIO – Black women experienced higher rates of breast cancer-related lymphedema than white women, and Black race was...
A Multimodal AI Model May Improve Recurrence Risk Stratification in Early Breast Cancer
New model provided better prognostic information for recurrence in HR-positive, HER2-negative breast cancer than the Oncotype DX 21-gene recurrence...
Circulating Tumor DNA May Help Predict Recurrence in Patients with Early Triple-Negative Breast Cancer
Study also indicated that a lack of ctDNA may signal improved outcomes for patients SAN ANTONIO — The presence...
Racial/Ethnic Minority Patients May Be Less Likely Than White Patients to Receive Palliative Care During Breast Cancer Treatment
Palliative care use increased among all racial/ethnic groups from 2004 to 2020 ORLANDO, Fla. – Despite a steady increase...
High-resolution Imaging Coupled With Elastography May Accurately Detect Breast Cancer in Surgical Margins
PHILADELPHIA – A high-resolution, three-dimensional imaging technique, when combined with quantitative measurement of tissue elasticity, could accurately detect cancer...
Coverage of Hormonal Breast Cancer Therapies Increased in States that Expanded Medicaid
NEW ORLEANS – An evaluation of breast cancer patients enrolled in Medicaid showed that states that expanded Medicaid during...
Addition of S-1 to Post-operative Endocrine Therapy Improves Outcomes for Patients with Hormone Receptor-positive, HER2-negative Breast Cancer
SAN ANTONIO — A post-operative combination of S-1, an oral fluoropyrimidine-based drug, with endocrine therapy significantly increased invasive disease-free survival...
ctDNA Levels After Neoadjuvant Therapy May Predict Breast Cancer Recurrence Better Than Pathologic Complete Response
ctDNA status after neoadjuvant therapy may also inform adjuvant therapy PHILADELPHIA – The presence of circulating tumor DNA (ctDNA)...
Circulating Tumor Cell Dynamics May Predict Treatment Response and Prognosis in Patients with Metastatic Breast Cancer
SAN ANTONIO – Early circulating tumor cell dynamics were associated with overall survival in patients with metastatic breast cancer,...
Surgery is Associated With Increased Survival for Patients With HER2+ Stage 4 Breast Cancer
Patients without insurance were less likely to receive surgery, increasing disparity in outcomes ATLANTA – Surgery was associated with...
Oxybutynin Decreased Frequency of Hot Flashes, Improved Quality of Life for Breast Cancer Survivors
SAN ANTONIO – Treatment with oxybutynin helped reduce the frequency and intensity of hot flashes for women who could...
Updated monarchE Trial Data Shows Abemaciclib Continues to Benefit Patients With High-risk, HR-positive, HER2-negative, Early-stage Breast Cancer
SAN ANTONIO – Extended follow-up data from the phase III monarchE trial showed that adding the cyclin-dependent kinase (CDK)...
Treatment Decision Guided by Circulating Tumor Cell Count May Improve Long-term Outcomes for Patients with Metastatic Breast Cancer
SAN ANTONIO – The use of circulating tumor cell (CTC) count to guide the choice between chemotherapy and endocrine...
Tucatinib Plus Trastuzumab Emtansine May Benefit Patients With Advanced or Metastatic HER2-positive Breast Cancer
SAN ANTONIO – A combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended progression-free survival...