Bloomberg Distinguished Professor
Johns Hopkins University Schools of Medicine, Engineering, and Public Health;
Director
Center for Epigenetics
Institute for Basic Biomedical Sciences
Baltimore, Maryland
For pioneering discoveries establishing the fundamental role of epigenetic alterations in cancer, including the identification of early widespread DNA methylation abnormalities and the role of genomic imprinting in tumor development. Dr. Feinberg’s research demonstrated that large-scale epigenomic alterations, including global DNA hypomethylation and partially methylated domains, contribute to tumor initiation, progression, and cellular heterogeneity, leading to the concept of epigenetic plasticity as a driver of cancer evolution. His discoveries established the epigenome as a central driver of cancer biology, identified causal epigenetic mechanisms for cancer risk and progression, and laid the foundation for new approaches to cancer detection, prevention, and therapeutic intervention.
The AACR-G.H.A. Clowes Award for Outstanding Basic Cancer Research was established by the AACR and Eli Lilly and Co. in 1961 to honor Dr. G.H.A. Clowes, who was a founding member of the AACR and a research director at Eli Lilly. The award is intended to recognize an individual who has made outstanding recent accomplishments in basic cancer research. To learn more, please visit the press release.
View Past Recipients.