Sarah-Maria Fendt, PhD
AACR Award for Outstanding Achievement in Basic Cancer Research

Sarah-Maria Fendt, PhD

Principal Investigator
Center for Cancer Biology, VIB
Professor of Oncology
VIB-KU Leuven Center for Cancer Biology
Leuven, Belgium

For seminal contributions to deciphering the role of metabolic rewiring during cancer invasion and metastasis and for defining the principles of metabolic regulation that enable cancer cell plasticity and heterogeneity. Dr. Fendt has described novel functions of phosphoglycerate dehydrogenase (PHGDH) in the initiation of cancer metastasis and discovered that lipid-rich environments promote metastasis by activating signaling pathways that subsequently drive therapeutic resistance.

The AACR Award for Outstanding Achievement in Basic Cancer Research was established by the AACR to recognize an early-career investigator for meritorious achievements in basic cancer research. The award is intended to recognize an individual who has not yet reached 46 years of age at the time of their award presentation.
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