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Innovators in Discovery

Home Patients, Caregivers, and Advocates Innovators

Cancer researchers, physician-scientists, and others are driving progress against cancer with discoveries that are advancing prevention and transforming care.

Dr. Elaine R. Mardis: Cancer Genome Pioneer

Dr. Elaine R. Mardis: Cancer Genome Pioneer

Drawn to the development of sequencing technologies, Dr. Mardis has been at the cutting edge of applying next-generation sequencing to understand the genetic blueprint of cancer.

Read more in Leading Discoveries magazine
Dr. Lillian L. Siu: At the Leading Edge of Drug Development

Dr. Lillian L. Siu: At the Leading Edge of Drug Development

For nearly three decades, Dr. Siu, AACR President, 2025-26, has been facilitating the development of novel cancer therapies and biomarkers for cancer patients.

Read more in Leading Discoveries magazine
Developing Cancer Therapies at the Intersection of Chemistry and Biology

Developing Cancer Therapies at the Intersection of Chemistry and Biology

Pioneering chemist and Fellow of the AACR Academy Carolyn R. Bertozzi, PhD, leads efforts to develop cancer therapeutics against “a different type of drug target.”

Learn more in AACR Stories
Dr. Robert A. Winn: Making Inroads Against Cancer Disparities

Dr. Robert A. Winn: Making Inroads Against Cancer Disparities

Throughout his career, Dr. Winn, the director of the VCU Massey Comprehensive Cancer Center, has been a driving force in the study of cancer disparities and implementing solutions.

Read more in Leading Discoveries magazine
Propelling Progress in Cancer Immunotherapy Research

Propelling Progress in Cancer Immunotherapy Research

Using funding from the AACR, early-career investigator Marco Ruella, MD, found a way to improve immunotherapy for B-cell acute lymphoblastic leukemia.

Learn more in AACR Stories
Targeting “Undruggable” Proteins That Drive Cancer

Targeting “Undruggable” Proteins That Drive Cancer

An AACR grantee, Raymond E. Moellering, PhD, uses chemistry to build “molecules that can go after undruggable protein targets” to treat cancers.

Learn more in AACR Stories
A Career Committed to Defeating Cancer

A Career Committed to Defeating Cancer

After Dr. Stephen Chanock’s brother and best friend, Foster, was diagnosed with a rare type of cancer, he dedicated his life to solving the problems of cancer.

Learn more in AACR Stories
Dr. Patricia M. LoRusso: Making Clinical Trials Better

Dr. Patricia M. LoRusso: Making Clinical Trials Better

Patricia M. LoRusso, DO, PhD (hc), FAACR, began her medical career in early-phase clinical trial development to test new cancer therapies. Thirty years later. Dr. LoRusso is still conducting early-phase clinical trials to test novel ways to treat cancer.

Read more in Leading Discoveries magazine
Dr. Chi Van Dang: Understanding the MYC Oncogene to Benefit Patients

Dr. Chi Van Dang: Understanding the MYC Oncogene to Benefit Patients

Chi Van Dang, MD, PhD, FAACR, was among the first to discover that MYC oncogenes regulate tumor metabolism and to establish MYC’s role in regulating the circadian rhythm and the immune system.

Read more in Leading Discoveries magazine
Dr. Philip D. Greenberg: Harnessing T Cells to Fight Cancer

Dr. Philip D. Greenberg: Harnessing T Cells to Fight Cancer

Philip D. Greenberg, MD, FAACR, was among a minority of cancer biologists initially attracted to the work of harnessing the immune system to treat cancer. He led a team that was among the first to take T cells from a cancer patient, isolate specific cancer-targeting T cells, expand the number of T cells in the lab, and infuse them back into the patient as a cell-based cancer immunotherapy.

Read more in Leading Discoveries magazine
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