Innovators in Discovery
Dr. Horwitz's contributions to the field encompass agents that have served as prototypes for some of the most important drugs currently in clinical use. Her most seminal contribution has been in the development of Taxol®, a drug isolated from the yew plant, Taxus brevifolia.
Lewis C. Cantley, PhD, leads a national effort targeting triple-negative breast cancer and ovarian cancer with a novel drug combination.
James P. Allison, PhD: Untangling the complexities of the immune system to pioneer cancer immunotherapy.
Elaine R. Mardis, PhD, spends a lot of her time studying molecules at the Institute for Genomic Medicine at Nationwide Children’s Hospital in Columbus, Ohio. What she sees is invisible to the naked eye, but her vision for what clinicians can do with the information they find in the genes of a cancer cell is clear.
Fellow of the AACR Academy John E. Dick, PhD, earns the 2020 Pezcoller Foundation-AACR International Award for Extraordinary Achievement in Cancer Research.
A leader in the study of how mutations affecting tumor-suppressor genes cause cancer, Dr. Kaelin's research has had major clinical implications for several forms of cancer, particularly kidney cancer. Dr. Kaelin, Sir Peter J. Ratcliffe, MD, FRS, and Gregg L. Semenza, MD, PhD, were awarded the 2019 Nobel Prize in Physiology or Medicine.
American Association for Cancer Research 2017-2018 President Elizabeth M. Jaffee, MD, seeks ways to expand AACR's efforts to nurture the next generation of cancer researchers and advance convergence science during her term leading the organization.
Phillip A. Sharp, PhD, Dr. Sharp who earned the 1993 Nobel Prize in Physiology or Medicine for his co-discovery of RNA splicing, didn’t set out to be a cancer researcher. But throughout his career, which spans nearly half a century, Dr. Sharp has been committed to developing collaborations that can generate new ways of thinking about cancer.
Dr. Suzanne L. Topalian of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins is working to find new ways to unleash the power of patients' immune systems to fight their cancers.
Dr. Northcott is exploring the role that blood vessels play in the growth of tumors and the delivery of chemotherapy.