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Frederick W. Alt, PhD

Frederick W. Alt, PhD

Howard Hughes Medical Institute
Boston, Massachusetts

Class of 2024

For revolutionizing the understanding of how genomic rearrangements occur, elucidating their role in cancer development and progression, and for discovering dihydrofolate reductase gene amplification in methotrexate-resistant cancer cells and MYCN amplification in neuroblastoma, as well as discovering the mechanisms regulating V(D)J recombination to form exons that encode antibody variable regions.

*Full-length biography in development

[Institutional affiliations listed for Fellows reflect those held at the time of their induction into the AACR Academy.]