Class of 2023
Scientific Area of Expertise: Chemical Biology, Growth Factor Signaling, K-Ras Drug Discovery
For revolutionary discoveries in the field of chemical genetics, including pioneering work to develop the first covalent inhibitors of KRAS G12C capable of therapeutically targeting a once-undruggable oncogene, which led to clinical trials involving various cohorts of lung, colon, and pancreas cancer patients and which notably expanded the armamentarium of available agents to combat cancer.