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Sara A. Courtneidge, PhD

Sara A. Courtneidge, PhD

Oregon Health & Science University
Portland, Oregon

Class of 2021

Scientific Areas of Expertise: Cancer Cell Biology; Invasion and Metastasis; Protein Kinases

For renowned contributions to the understanding of oncogenic transformation including discovering that RSV v-Src transforming protein and c-Src are plasma membrane-associated, defining the activation mechanism of the c-Src tyrosine kinase; discovering that c-Src is involved in polyomavirus transformation, which revolutionized the DNA tumor virus field; and identifying Tks4 and Tks5 adaptor proteins as Src substrates that trigger invadopodia formation and protease secretion essential for tumor cell invasion.