The GENIE Registry is a continuously evolving, publicly available real-world data resource, housing: 

230,000+ clinical-grade genomic samples from 200,000+ patients 

30,000 new patients added annually 

High-fidelity clinico-genomic data from academic tertiary referral centers 

International representation (U.S. and ex-U.S. patient populations) 

Why It Matters 

The breadth and quality of GENIE data make it an essential resource for: 

Biomarker Discovery: Identifying and validating predictive biomarkers. 

Clinical Trial Feasibility: Informing trial design and patient selection. 

Regulatory-Grade RWE: Supporting real-world evidence (RWE) submissions. 

Unlike commercial datasets primarily sourced from community practices, the GENIE Registry reflects real-world clinical practice at leading academic cancer centers, ensuring data quality, diversity, and regulatory relevance.