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SU2C Dream Team Translational Research Grant | Grant Status - Open

Grant Amount$ 10,000,000 USD

Expected Number of
Funded Grants

1

Grant Term

3 Year(s)

Letter of Intent Deadline

9/5/2017 12:00:00 PM

Letter of Intent Deadline Time Zone

Eastern Standard Time

Letter of Intent Notification Date

10/2017

Application Deadline

1/16/2018 12:00:00 AM

Application Deadline Time Zone

Eastern Standard Time

Decision Date

3/2018

Description

The Stand Up To Cancer Dream Team Translational Research Grant will fund a translational cancer research project that will address critical problems in patient care, including prevention strategies for those at risk, and deliver near-term patient benefit through investigation by a multidisciplinary, multi-institutional, collaborative Dream Team of expert investigators.
The ideas may focus on particular organ sites, patient populations (such as pediatrics) or on innovative methods of treatment. Projects must be designed to accelerate the application of new preventive, diagnostic or therapeutic approaches to the clinic (i.e., lead to patient involvement within 2-3 years from the beginning of the grant). Proposals for Dream Team research projects must present plans indicating how the work will be translated into the clinic. The ideas should be based on perceived opportunities for success as well as high-priority areas with a critical need for rapid progress beyond current medical care.
Proposals for Dream Team research projects must present plans indicating how the work will be translated into the clinic. The ideas should be based on perceived opportunities for success as well as high-priority areas with a critical need for rapid progress beyond current medical care.
Through a partnership with leading health care research and innovation collaborative OptumLabs, each team will have the ability to conduct research using OptumLabs’ proprietary database of de-identified claims and electronic health record data, analytic tools, and research support to pursue the proposed goals of the Dream Team. Appendix A in the Program Guidelines provides more information on OptumLabs. Collaboration with OptumLabs provides researchers access to real world data to support health service and population health research.
OptumLabs will be conducting information sessions for applicants who are interested in learning more about the OptumLabs Data Warehouse. If you would like more information or to register to attend, please email proposals.optumlabs@optum.com by August 1, 2017 and include your name, institution and Dream Team Leader name. OptumLabs will contact interested parties about next steps, including dates and times of the information sessions.

Eligibility Criteria

To maximize creativity, innovation, and collaboration, the Dream Team must include laboratory and clinical researchers, senior and/or young investigators, and senior scientists who have not worked together in the past.

Each Team will consist of a Dream Team Leader, a Dream Team Co-leader, no more than four additional Dream Team Principals, a Dream Team Project Manager, and at least two Advocates, with no more than six but a minimum of three participating institutions.

The Dream Team Leader, Dream Team Co-leader, Dream Team Principals, Dream Team Project Manager, and Advocates are collectively referred to as Key Personnel. The Dream Team Leader, Co-leader and Principals, must have acquired a doctoral or medical degree, and must be independent investigators affiliated with an academic, medical, or research institution.

The Dream Team Leader and Co-leader are expected to each dedicate at least 20 percent (or 40 percent combined) of their time and effort to the Dream Team research project. Dream Team Principals must each dedicate at least 10 percent of their time and effort to the Dream Team research project.

No Dream Team will have more than one Dream Team Leader, Co-leader, or Principal from any given institution at the time of their initial appointment on the Team. Except from the Project Manager and Advocates, no more than two Key Personnel may be from affiliated institutions. It is expected that additional Investigators from the Dream Team Leader’s, Co-leader’s or Principals’ institutions may be involved in the Dream Team research project in some other capacity, and there is no limit to the number of Investigators from each of these institutions that may contribute to the Dream Team project.

Employees or subcontractors of for-profit industry are not eligible to serve as a Dream Team Leader, Co-leader, or Principal, however their participation as Collaborators is encouraged, where appropriate, to foster the development of novel diagnostic and treatment strategies. No grant funds may be directly awarded to Collaborators or any other individual working within a U.S. government institution/agency or a for-profit industry. Confidentiality and intellectual property issues must be negotiated with Collaborators prior to their participation in a Dream Team research project.


Young Investigators, including junior faculty, postdoctoral fellows, clinical research fellows, or any other researchers working under the direction of a scientific mentor, are not eligible to serve as a Dream Team Leader, Co-leader, or Principal; however, their participation in the Dream Team research projects is encouraged.

There are no citizenship or residency status restrictions. Neither members of the SU2C SAC nor members of their individual laboratories are eligible for funding as part of the Stand Up To Cancer Dream Team Translational Research Grant. Key Personnel should not be funded on more than one SU2C-sponsored Dream Team grant. Except for the Dream Team Leader and Co-leader, scientists may be funded concurrently on SU2C and SU2C Canada grants. No more than 50 percent of the Principals (including Leader and Co-leader) from a previous Dream Team may apply as a group on a new Dream Team proposal.

Citizenship Requirements

​There are no citizenship or residency status restrictions.

AACR Membership Requirements

None.

Application Instructions

​The AACR requires applicants to submit an electronic Letter of Intent via proposalCENTRAL by 12:00 pm (noon), Eastern Time on Tuesday, September 5, 2017 using the proposalCENTRAL website at http://www.proposalcentral.altum.com

The Program Guidelines and Application Instructions are available in PDF format.

The Call for Ideas Document is available here.