Arthur B. Pardee, PhD
Professor of Biological Chemistry and Molecular Pharmacology Emeritus, Harvard Medical School, Cambridge, Massachusetts
An icon to a generation of scientists, Dr. Pardee has done much to advance our understanding of molecular biology. He took part in what has become known as the “PaJaMo (Pardee/Jacob/Monod) experiment” at the Institut Pasteur in Paris in the late 1950s, which led scientists to question how genetic information could be converted to protein so quickly. This in turn led to the discovery in 1960 of messenger RNA (mRNA). In the 1970s he discovered the restriction point (sometimes called the Pardee point) in which a cell commits itself to certain cell cycle events during the G1cycle. He also invented differential display, a method to detect the mRNAs expressed in a given cell type, a method that has been widely used by researchers to isolate genes of interest.
Dr. Pardee is the recipient of numerous awards and has held office in many professional organizations. As a leader of the AACR in the 1980’s, he worked to strengthen programs in molecular biology and genetics, which have attracted many molecular biologists over the years and are areas that permeate the Association’s scientific programs today.
1999 Distinguished Alumni Award, California Institute of Technology1998 Boehringer Mannheim Award1985-1986 President, AACR1983-1986 Board of Directors, AACR1980 FASEB 3M Award1980 President, American Society of Biological Chemists1975 Professor, Biological Chemistry and Molecular Pharmacology, Harvard Medical School, and Dana-Farber Cancer Institute, Boston MA1975 Rosenstiel Medal1974 Elected Member, Institute of Medicine1973 Sir H. A. Krebs Medal, Federation of European Biochemical Societies1968 Elected Member, National Academy of Sciences, Washington, D.C.1963 Elected Fellow, American Academy of Arts and Sciences1961-1974 Professor of Biochemical Sciences, Princeton University1960 Paul Lewis Award, American Chemical Society1947 PhD, California Institute of Technology