In This Section

Program: Thursday, July 23

Tuesday, July 21 Wednesday, July 22 Friday, July 24

Please note that this meeting will take place as an in-person event in Boston, Massachusetts and will not live-stream content for virtual participation. The meeting content will be recorded and made available as an on-demand program after the conference.

All presentations are scheduled to be live, in-person presentations at the date and time specified below unless noted otherwise. Program in progress.

*-Short talk from proffered abstract

Thursday, July 23

Thursday, July 23

Networking Breakfast

7-8 am | Independence Ballroom West

Keynote Lecture

8-9 am | Grand Ballroom

  • 8:05 a.m. | Keynote Lecture
    William R. Sellers, Broad Institute of MIT and Harvard, Cambridge, Massachusetts
  • 8:45 a.m. | Q&A   

Break

9-9:15 a.m. | Grand Ballroom Prefunction

Plenary Sessions 3-4

9:15-11:15 a.m.

Plenary Session 3: AI in Oncology: Facts and Hopes

Grand Ballroom
Session Chair: Sarah Skerratt, Chief Research Officer, Isomorphic Labs, London, United Kingdom

  • 9:20 a.m. | Sarah Skerratt
  • 9:50 a.m. | Jorge Reis-Filho, AstraZeneca, New York, New York
  • 10:20 a.m. | Benjamin Haibe-Kains, UHN Princess Margaret Cancer Centre, Toronto, Ontario, Canada
  • 10:50 a.m. | Panel Discussion

Plenary Session 4: From RAS Inhibitors to RAS Degraders

Constitution Ballroom A
Session Chair: Rona Yaeger, Memorial Sloan Kettering Cancer Center, New York, New York

  • 9:20 a.m. | Development of KRAS G12D degraders
  • Kathryn Smith, Arvinas, New Haven, Connecticut
  • 9:40a.m. | Speaker to be announced
  • 10 a.m. | Novel molecular glue degraders to target KRAS mutants
    Anita C. Bellail, HB Therapeutics, Indianapolis, Indiana
  • 10:20 a.m. | Ignacio Garrido-Laguna, University of Utah Huntsman Cancer Institute, Salt Lake City, Utah
  • 10:50 a.m. | Panel Discussion

Break

11:15-11:30 a.m.

Concurrent Roundtables 1-2

11:30 a.m.-12:30 p.m.

Roundtable 1: Policy

Constitution Ballroom A

  • 11:30 a.m. | Introductions
  • 11:40 a.m. | Discussion
  • 12:15 p.m. | Q&A

Roundtable 2: Accelerating Investigator-Initiated Clinical Trials with Team Science

Constitution Ballroom B
Moderator: Elizabeth A. Jaffee, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland

  • 11:30 a.m. | Introductions
  • 11:40 a.m. | Discussion
  • 12:15 p.m. | Q&A

Lunch on Own

12:30-2:45 p.m.

Start-Up Shark Tank 1

3-4:30 p.m.

Break

4:30-4:45 p.m. | Grand Ballroom Prefunction

Drugging the Surfacesome Sessions 1-3

4:45-6:15 p.m.

Drugging the Surfacesome 1: Drug conjugates for solid tumors – Choosing the Right Modality for the Right Target

Grand Ballroom
Session Chair: Raffaele Colombo, Zymeworks Inc., Vancouver, British Columbia, Canada

  • 4:50 p.m. | Advancements in small molecule drug conjugates with cytotoxic payloads and radioligands
    Dario Neri, ETH Zurich, Zurich, Switzerland
  • 5:10 p.m. | Radioconjugated antibodies and antibody fragments as precision therapeutics
    Andrew M. Scott, Olivia Newton-John Cancer Research Institute, Heidelberg, VIC, Australia
  • 5:30 p.m. | Optimizing payload delivery: Lessons from ADC mechanisms and clinical translation
    Jamie Rich, Zymeworks Inc., Vancouver, British Columbia, Canada
  • 5:50 p.m. | Molecular imaging in drug development and as a biomarker to guide treatment decisions: What we learn from imaging antibody-based agentsin patients
    Elisabeth De Vries, University Medical Center Groningen, Groningen, The Netherlands

Drugging the Surfacesome 2: Multispecifics

Constitution Ballroom A
Session Chair: Daniel S. Chen, Synthetic Design Lab, San Carlos, California

  • 4:50 p.m. | Multifunctional multivalent multispecific therapeutics
    Daniel S. Chen
  • 5:10 p.m. | Multispecific protein expression and proximity therapeutics
    Pamela Holland, InduPro, Seattle, Washington
  • 5:30 p.m. | Speaker to be announced
  • 5:50 p.m. | Panel Discussion

Drugging the Surfacesome 3: Radionucleotides

Constitution Ballroom B
Session Chair: H. Charles Manning, The University of Texas MD Anderson Cancer Center, Houston, Texas

  • 4:50 p.m. | Speaker to be announced
  • 5:10 p.m. | Speaker to be announced
  • 5:30 p.m. | Speaker to be announced
  • 5:50 p.m. | Panel Discussion

Poster Session B / Reception

6:15-8:45 p.m. | Back Bay Ballroom

Evening off / Dinner on own

8:45 p.m.