Please note that this special conference will take place as an in-person event in Boston and will not live-stream content for virtual participation. The conference content will be recorded and made available as an on-demand program after the conference.

All presentations are scheduled to be live, in-person presentations at the date and time specified below unless noted otherwise. Program in progress.

*-Short talk from proffered abstract

Tuesday, September 22

• Opening Plenary Session

Wednesday, September 23

• Plenary Session 1: Cell States, Plasticity, and Metastatic Progression
• Plenary Session 2: Emerging Mechanisms and Therapeutic Vulnerabilities
• Plenary Session 3: Developmental Pathways in Pediatric Cancer
• Plenary Session 4: Organized by the Pediatric Cancer Working Group
• Poster Session A

Thursday, September 24

• Plenary Session 5: Tumor Microenvironment and Immunity
• Plenary Session 6:  Advances in Immunotherapy for Pediatric Cancer
• Plenary Session 7: Tumor Genomics, Predisposition, and Mosaicism
• Poster Session B

Friday, September 25

• Plenary Session 8: Cancer Cell Biology, Organelle Function, and Metabolism
• Plenary Session 9: Title to be announced

Opening Plenary Session

5-7 p.m.

• 5 p.m. | Charles Mullighan, St. Jude’s Children’s Hospital, Memphis, Tennessee
• 6 p.m. | AACR-St. Baldrick’s Foundation Pediatric Cancer Research Fellowship Awardee Lecture
  Nicole Michmerhuizen, University of Rochester Medical Center, Rochester, New York

Opening reception

7-8:30 p.m.

CONTINENTAL BREAKFAST

7-8 a.m.

plenary Session 1: Cell States, Plasticity, and Metastatic Progression

8-9 a.m.

• 8 a.m. | David M. Langenau, Mass General Brigham, Boston, Massachusetts
• 8:30 a.m. | Single-cell regulatory network analysis of cell state heterogeneity and remodeling under therapy to design treatment strategies in osteosarcoma
  Jovanna Pavisic, Memorial Sloan Kettering Cancer Center, New York, New York
• 9 a.m. | Poul Sorensen, University of British Columbia, Vancouver, British Columbia, Canada

break

10-10:30 a.m.

Plenary Session 2: Emerging Mechanisms and Therapeutic Vulnerabilities

10:30 a.m.-12:30 p.m.

• 11 a.m. | Immunotherapeutic approaches to intracellular oncofetal proteins
  John Maris, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
• 11:30 a.m. | Annie A. Huang, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada

lunch on own/free time

12:30-2:30 p.m.

PLENARY Session 3: Developmental Pathways in Pediatric Cancer

2:30-4:30 p.m.

• 2:30 p.m. | Identity theft: origins of rhabdomyosarcoma
  Mark Hatley, St. Jude’s Children’s Hospital, Memphis, Tennessee
• 3:30 p.m. | Kim Stegmaier, Dana Farber Cancer Institute, Boston, Massachusetts

Plenary Session 4: title to be announced

Organized by the Pediatric Cancer Working Group

4:45-6:45 p.m.

Poster session A

7-9 p.m.

CONTINENTAL BREAKFAST

7-8 a.m.

Plenary Session 5: Plenary Session 5: Tumor Microenvironment and Immunity

8-10 a.m.

• 8:30 a.m. | Marking and modulating microenvironmental reprogramming in pediatric cancer progression
  Rosandra Kaplan, National Cancer Institute, Bethesda, Maryland

break

10-10:30 a.m.

Plenary Session 6: Advances in Immunotherapy for Pediatric Cancer

10:30 a.m.-12:30 p.m.

• 10:30 a.m. | Crystal Mackall, Stanford University, Stanford, California
• 11 a.m. | Javed Khan, National Cancer institute, Bethesda, Maryland
• 11:30 a.m. | Addressing challenges with CAR T cells for AML
  Terry Fry, Children’s Hospital Colorado Anschutz, Aurora, Colorado 

lunch on own/free time

12:30-2:15 p.m.

Plenary Session 7: Tumor Genomics, Predisposition, and Mosaicism

2:15-4:15 p.m.

• 2:15 p.m. | New frontiers in childhood cancer predisposition: Harnessing genomics for early detection and tumor interception
  David Malkin, SickKids, Toronto, Ontario, Canada
• 2:45 p.m. | Suzanne P. MacFarland, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
• 3:15 p.m. | Olivier Delattre, Inserm/Institut Curie, Paris, France

Poster Session B

4:30-6:30 p.m.

CONTINENTAL BREAKFAST

7-8:30 a.m.

Plenary Session 8: Cancer Cell Biology, Organelle Function, and Metabolism

8-10 a.m.

• 8 a.m. | New insights into drug resistance
  Alejandro Gutierrez, St. Jude’s Children’s Hospital, Memphis, Tennessee
• 8:30 a.m. | Miguel N. Rivera, Mass General Brigham, Boston, Massachusetts
• 9 a.m. | Multi-omic integration and lipid dependency in Medulloblastoma
  Olivier Ayrault, Institut Curie, Paris, France                    

break

10-10:30 a.m.

Plenary Session 9: Title to be Announced

10:30 a.m.- 12:30 p.m.

Closing Remarks 

12:30-12:45 p.m.