Phillip A. Sharp, PhD
Institute Professor, Massachusetts Institute of Technology and Faculty Member of the David H. Koch Institute for Integrative Cancer Research and Department of Biology Cambridge, Massachusetts
A world leader in molecular biology and biochemistry, Dr. Sharp’s landmark achievement was the co-discovery of RNA splicing, which led to his being awarded the 1993 Nobel Prize in Physiology or Medicine. This work provided the first indication of the startling phenomenon of “discontinuous genes” in mammalian cells. It fundamentally changed scientists’ understanding of the structure of genes. He currently investigates the processes by which RNA molecules act as switches to turn genes on and off (RNA interference), which could lead to a new class of cancer therapeutics.
Dr. Sharp has received many awards and over 15 honorary degrees and is a central figure in biotechnology and drug discovery. He co-founded Biogen (now Biogen Idec) in 1978 and Alnylam Pharmaceuticals in 2002 and has served as a thought leader for numerous think tanks and advisory boards that have helped determine the future of cancer research. For example, he chairs the Scientific Advisory Committee for the SU2C-AACR Dream Team Program and has served as a member of the National Cancer Advisory Board and the Presidential Committee for Advice on Science and Technology.
2013 President, American Association for the Advance of Science2011 Elected Foreign Member, Royal Society of London2010 AACR-Margaret Foti Award for Leadership and Extraordinary Achievements in Cancer Research2006 Inaugural Double Helix Medal for Scientific Research, Cold Spring Harbor Laboratory2006 AACR-Irving Weinstein Distinguished Award2004 National Medal of Science, National Science Foundation2000-2002 Chairman, National Cancer Advisory Board, National Cancer Institute1999 The Benjamin Franklin Medal for Distinguished Achievement in the Sciences, American Philosophical Society1993 Nobel Prize in Physiology or Medicine1991 Elected Member, Institute of Medicine1988 Albert Lasker Basic Medical Research Award1986 The New York Academy of Sciences Award in Biological and Medical Sciences1983 Elected Member, National Academy of Sciences, Washington, D.C.1983 Elected Fellow, American Academy of Arts and Sciences1969 PhD, University of Illinois