Bhalchandra Mirlekar, PhD

Bhalchandra Mirlekar, PhD

Postdoctoral Research Associate
University of North Carolina at Chapel Hill
North Carolina

Dr. Bhalchandra Mirlekar is an immunologist with a deep and long-lasting interest in how body’s immune response shapes cancer and tumor-microenvironment. He is addressing the role of B cells in regulating anti-tumor immunity in pancreatic cancer, with developing new immune-based therapy options for this deadly malignancy. His pre-clinical studies show blockade of IL-35 producing B cells makes pancreatic tumor more responsiveness towards immune-checkpoint blockade therapy. Therefore, his current research focused on design of combinatory therapeutic biologicals such as anti-IL-35 with anti-PD-1 or anti-CTLA-4 cancer immunotherapy along with biomarkers of response to therapy for effective and better treatment of pancreatic cancer patients.