David C. Lyden, MD, PhD
AACR-Princess Takamatsu Memorial Lectureship

David C. Lyden, MD, PhD

Stavros S. Niarchos Professor of Pediatrics and Cell and Developmental Biology
Director of the Physician-Scientist Training Program
Drukier Institute for Children’s Health
Meyer Cancer Center
Weill Cornell Medicine
New York, New York

For pioneering discoveries defining how primary tumors systemically promote metastasis through the formation of pre-metastatic niches in distant organs. Dr. Lyden’s research demonstrated that tumor-derived extracellular vesicles and exomeres, together with bone marrow-derived progenitor cells, remodel distant microenvironments and determine organ-specific metastatic tropism. His work has advanced understanding of metastatic dissemination and revealed links between tumor-derived vesicles, cancer-associated thrombosis, and systemic effects of cancer.

The AACR-Princess Takamatsu Memorial Lectureship is awarded to a scientist whose novel and significant fundamental scientific work has had or may have a far-reaching impact on the detection, diagnosis, treatment, or prevention of cancer, and who embodies the dedication of the Princess to outstanding cancer research and advances that emanate from multinational collaborations. Her Imperial Highness Princess Kikuko Takamatsu was personally instrumental in promoting progress against cancer. She became a champion of these causes following her mother’s death from bowel cancer in 1933 at the young age of 43. To learn more, please visit the press release.

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