AACR-Novocure Tumor Treating Fields in NSCLC Research Grant
The AACR-Novocure Tumor Treating Fields in NSCLC Research Grant represents a joint effort to promote and support independent investigators to conduct innovative research focused on Tumor Treating Fields (TTFields; intermediate frequency, low intensity, alternating electric fields that disrupt cell division in cancer cells) in Non-Small Cell Lung Cancer (NSCLC). This grant is intended to provide a deeper understanding of the mechanisms of action of this novel anti-cancer treatment modality and to accelerate the development of new treatment strategies to advance therapeutic options for NSCLC. Research projects should examine the use of TTFields as a therapeutic modality in NSCLC.
The grant provides $350,000 over three years ($125,000 for year 1 and 2, and $100,000 for year 3) for expenses related to the research project, which may include salary and benefits of the grant recipient and any collaborators*, postdoctoral or clinical research fellows, graduate students and/or research assistants; research/laboratory supplies; equipment; travel; publication charges for manuscripts that pertain directly to the funded project; other research expenses; and indirect costs. (*Note that interlaboratory collaboration is encouraged.)
Download Program Guidelines and Application Instructions here.
Research proposals must incorporate use of the Inovitro® system into the experimental design. For grant recipients who are affiliated with institutions that do not currently hold a Materials Transfer Agreement (MTA) with Novocure for use of its devices, Novocure will provide this system to complete the research. For additional details, please see the MTA and Terms and Conditions. If selected for funding, Novocure will work with the institution to execute an MTA.
Research projects should examine the use of TTFields as a therapeutic modality in NSCLC. Proposals may include 1) Basic and translational approaches, promoting the transition of TTFields in vitro work into in vivo systems, 2) Studies that link preclinical and clinical data, or 3) Studies with ability to translate into the clinic for the treatment of NSCLC.
Projects focused on one or more of the areas outlined below are strongly encouraged:
- Key cancer-related signaling and cellular pathways
- Metabolic effects of TTFields
- Studies that include Omics data (genomics, transcriptomic, proteomics)
- TTFields immunological aspects in NSCLC and the potential combination with immunotherapy
- Combinational studies with approved agents, preferably to include mechanistic aspects
Institutions may submit multiple applications for the AACR-Novocure Career Development Award for Tumor Treating Fields in Ovarian Cancer Research and the AACR-Novocure Tumor Treating Fields in NSCLC Research Grant for multiple applicants. However, no more than one applicant will be awarded from the same department of an institution.
Applicants must have a doctoral degree (PhD, MD, MD/PhD, or equivalent) in a related field and not currently be a candidate for a further doctoral degree.
Investigators may submit only one application for the AACR-Novocure Tumor Treating Fields in NSCLC Research Grant but may concurrently apply for other AACR grants. However, applicants are expected to accept the first grant they are awarded. Individuals may accept and hold only one AACR grant at a time.
Employees or subcontractors of a U.S. government entity or for-profit private industry are not eligible.
Employees or subcontractors of a U.S. government entity or for-profit private industry may serve as Collaborators, but no grant funds may be directed towards these individuals.
Current and past recipients of an AACR-Novocure Tumor Treating Fields Research Grants are not eligible to apply. Collaborators or other participants of an active AACR Novocure grant (at the time of application deadline) are also not eligible to apply.
Current Grantees of other AACR Research Grants may apply if their current grant ends before the start of the grant term of this funding opportunity i.e., December 1, 2022, and must be up to date with all reporting requirements to be considered eligible.
Postdoctoral or clinical research fellows or the equivalent who are working under the auspices of a scientific mentor are not eligible to apply. Qualified fellows are invited to apply for an AACR Fellowship.
Members of the Scientific Review Committee are not eligible to apply for an AACR-Novocure Tumor Treating Fields in NSCLC Research Grant.
All applicants with questions about eligibility should contact the AACR’s SRGA at [email protected] before submitting an application.
There are no citizenship requirements; however, by submitting an application for this grant, an applicant applying from an institution located in a country in which they are not a citizen or a permanent resident assures that the visa status will provide sufficient time to complete the project and grant term at the institution from which they applied.
Applicants must be AACR Active members. Nonmembers interested in this grant opportunity must submit a satisfactory application for AACR Active membership by the application deadline. Nonmembers can apply for membership online. Members can renew their membership through myAACR to bring their membership current. You will need your logon (email address) and password to access the member portal. If you require assistance logging in, please submit a help form. Lapsed members must be members in good standing by the application deadline and should contact the Membership Department at [email protected] for assistance
The AACR requires applicants to submit an online application by 1:00 p.m. U.S. Eastern Time on Tuesday, September 20, 2022 using the ProposalCentral website at https://proposalcentral.com/.
Download Program Guidelines and Application Instructions here.