In This Section

SU2C-Cancer Research UK-Lustgarten Foundation Pancreatic Cancer Dream Team Translational Research Grant

Grant Amount $12,000,000 USD
Grant Term3 Years
Start of Grant Term01/01/2016
Letter of Intent Deadline05/06/2015 12:00 PM (AST)
Letter of Intent Notification DateJune 17, 2015
Application Deadline08/24/2015 12:00 PM (AST)
Decision Date10/19/2015 5:00:00 PM
Description

The American Association for Cancer Research (AACR), on behalf of Stand Up To Cancer (SU2C), Cancer Research UK, and the Lustgarten Foundation calls upon members of the cancer community to contribute their ideas to the groundbreaking Stand Up to Cancer-Cancer Research UK-Lustgarten Foundation Pancreatic Cancer Dream Team Translational Research Grant.

We invite the submission of ideas for a translational cancer research project that will address critical problems in pancreatic cancer and positively impact patients in the near future. The project should include interventions in prevention, diagnosis, or treatment of pancreatic cancer, and deliver near-term patient benefit through investigation by a multidisciplinary, multi-institutional, transatlantic, synergistic Dream Team of expert investigators. The project must be designed to accelerate therapeutic application to the clinic (i.e., lead to patient involvement within 2-3 years from the beginning of the grant). Proposals for this Dream Team research project must present plans indicating how the work will be translated into the clinic. The ideas should be based on perceived opportunities for success as well as high-priority areas with a critical need for rapid progress beyond current medical care.

Letters of Intent will be reviewed by the SU2C-Cancer Research UK-Lustgarten Foundation Joint Scientific Advisory Committee (JSAC), and Teams with the most promising idea submissions will be invited to submit full proposals. The JSAC will select an SU2C-Cancer Research UK-Lustgarten Foundation Pancreatic Cancer Dream Team from the invited proposals. The SU2C-Cancer Research UK-Lustgarten Foundation Pancreatic Cancer Dream Team will be awarded up to $12 million over the 3-year term of the grant.

Research Project Criteria

This grant is for a translational cancer research project that addresses critical problems in pancreatic cancer patient care. The project must include interventions in prevention, diagnosis, or treatment of pancreatic cancer and deliver near-term patient benefit through investigation by a multidisciplinary, multi-institutional, transatlantic, synergistic Dream Team of expert investigators. The project must be designed to accelerate therapeutic application to the clinic (i.e., lead to patient involvement within 2-3 years from the beginning of the grant). Proposals for Dream Team research projects must present plans indicating how the work will be translated into the clinic. The ideas should be based on perceived opportunities for success as well as high-priority areas with a critical need for rapid progress beyond current medical care. At least one Dream Team Member (Leader, Co-leader, or Principal) must be from a U.K. Institution and at least 25% of the grant must be used to support research within the United Kingdom.

Eligibility Criteria

Each Team will consist of a Dream Team Leader, a Dream Team Co-leader, one of whom should be expert in translational research, no more than four additional Dream Team Principals, and at least two Advocates. At least one member, the Leader, Co-leader or a Principal, must be from an institution within the United Kingdom. No Dream Team will have more than one Leader or Principal from any given institution at the time of their initial appointment on the Team. No more than two Leaders or Principals may be from affiliated institutions. It is expected that additional Investigators from the Dream Team Leader's, Co-leader's or Principal's institutions may be involved in the Dream Team research project, and there is no limit to the number of Investigators from each of these institutions.

There are no citizenship or residency status restrictions. Neither members of the SU2C-Cancer Research UK-Lustgarten Foundation Joint Scientific Advisory Committee (JSAC), nor members of their individual laboratories are eligible for funding as part of the SU2C-Cancer Research UK-Lustgarten Foundation Pancreatic Cancer Dream Team. A scientist may not be funded on more than one SU2C-sponsored Dream Team grant. No more than fifty percent of the Principals (including Leader and Co-leader) from a previous Dream Team may apply as a group on a new Dream Team proposal.

Citizenship Requirements

None

AACR Membership Requirements

None

Application Instructions

Letters of Intent must be submitted by 12:00 p.m. (noon) U.S. Eastern Time on May 6, 2015, using the proposalCENTRAL website at https://proposalcentral.altum.com/default.asp?GMID=39.