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Lieping Chen, MD, PhD

Lieping Chen, MD, PhD

Yale University School of Medicine
New Haven, Connecticut

Class of 2021

Scientific Areas of Expertise: Cancer Biology; Cancer Immunotherapy; T Cell Activation and Tolerance

For his unrivaled leadership in the field of PD-L1 biology, including his fundamental research that led to the cloning of B7-H1(PD-L1), subsequent demonstration of the immunosuppressive functions of the B7-H1/PD-1 signaling pathway, the use of antibody blockade of this pathway as a cancer immunotherapy, and his pivotal discovery of costimulation as a mechanism to improve tumor immunity, which has since led to the development of breakthrough treatments for human cancer.