AACR-Loxo Oncology Pediatric Cancer Research Fellowship

The AACR-Loxo Oncology Pediatric Cancer Research Fellowship represents a joint effort to encourage and support a postdoctoral or clinical research fellow to conduct pediatric cancer research and to establish a successful career path in this field. Funded research can be basic, translational, clinical, or epidemiological in nature.

2019 Grantee

Meenal Datta, PhD

Meenal Datta, PhD

Research Fellow
Massachusetts General Hospital
Boston, Massachusetts
Reprogramming the medulloblastoma microenvironment to improve treatment

Research
Medulloblastoma (MB) is one of the most common and devastating brain tumors in children. Safer and more effective treatments for MB are urgently needed. Dr. Datta aims to reveal the underlying abnormalities in the MB tumor microenvironment that drive tumor progression and treatment resistance. Targeting these resistance mechanisms, including immunosuppressive signaling pathways, in combination with rapidly translatable low-dose radiotherapy, can boost anti-tumor immunity and response to novel immunotherapies.

Biography
Dr. Datta received her PhD in chemical and biological engineering from Tufts University. She is currently a postdoctoral researcher at Massachusetts General Hospital and Harvard Medical School, where she is working on reprogramming the tumor microenvironment to improve response to immunotherapy. Prior to this AACR-Loxo Oncology fellowship, she received numerous training awards including the AACR Scholar-in-Training Award, the Helmsley Charitable Trust Fellowship, and the NIH F31 Predoctoral Fellowship.

Acknowledgement of Support
I am humbly honored to be awarded the AACR-Loxo Oncology Pediatric Cancer Research Fellowship. With the support of this prestigious award, I will be able to successfully complete my postdoctoral training and lay the foundation for my future career as an independent academic researcher dedicated to discovering new and translatable approaches for cancer treatment.