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AACR Grantees Present Their Work at the 2022 AACR Annual Meeting

We are extremely proud of our past and present AACR grantees who have been selected to present their work via oral and poster presentations. We invite you to attend their talks and visit their posters to hear of the progress they have made with support, at least in part, from AACR and its funding partners.

David A. Tuveson, MD, PhD

April 10th

Opening ceremony

7:45 – 9:45 a.m., Hall B-C

David A. Tuveson, MD, PhD, AACR President and 2003 AACR-PanCAN Career Development Award in Pancreatic Cancer Research recipient

Poster presentations:

Late-Breaking Research: Tumor Biology 1

Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer progression

Jason J. Northey, PhD, 2015 AACR Basic Cancer Research Fellow and 2017 AACR-Janssen Fellow in Cancer Interception Research

Nanoparticles and Other Novel Strategies for Drug Delivery

Blood brain barrier (BBB) disruption by tumor treating fields (TTFields) in a human 3D in vitro model

Carsten Hagemann, PhD, 2020 AACR-Novocure Tumor Treating Fields Research Grant recipient

Nanotechnology Drug Delivery

Self-assembling nanoparticles: A novel approach for targeted cancer treatment using tumor treating fields

Preshita Prafulla Desai, PhD, 2019 AACR-Novocure Tumor Treating Fields Research Fellow

April 11th

oral presentations:

Predictive Biomarkers for Precision Radiation Oncology

10:15 -11:45 a.m., Room 343-345

Julie Schwarz, MD, PhD, 2019 AACR-Bristol Myers Squibb Midcareer Female Investigator Grant

Epigenetic Alterations as Cancer Therapeutic Targets

12:30-2:00 p.m., New Orleans Theater A

Daniel Herranz, PharmD, PhD, 2022 AACR NextGen Star and 2021 AACR-Bayer Innovation and Discovery Grant recipient

Next-Gen Genetically Engineered Mouse Models: Dedicated to the Memory of Beatrice Mintz

2:30-4:30 p.m., Room 278-282

Valerie Phoebe O’Brien, PhD, 2018 Debbie’s Dream Foundation—American Association for Cancer Research (AACR) Gastric Cancer Research Fellowship, in memory of Sally Mandel recipient

Poster presentation

Spatial Proteomics and Transcriptomics

Spatial omic changes of malignant pleural mesothelioma following treatment using tumor-treating fields

Emil Lou, MD, PhD, 2019 AACR-Novocure Tumor Treating Fields Research Grant recipient

April 12th

oral presentations:

AACR Gertrude B. Elion Cancer Research Award Lecture

12:00 – 12:30 p.m., Room 220-222

Alison M. Taylor, PhD, 2021 AACR Gertrude B. Elion Cancer Research Award recipient

Novel Cellular Mechanisms for Immune Evasion in Cancer

2:30 – 4:30 p.m., New Orleans Theater A

Raphael Mattiuz, PhD, 2021 AACR-AstraZeneca Immuno-oncology Research Fellow

poster presentations:

Cancer Genomics 4

Identification of predisposition and progression gastric cancer biomarkers in Latinos

Ana Estrada-Florez, PhD, 2021 AACR Fellowship to Further Diversity, Equity, and Inclusion in Cancer Disparities Research recipient

Molecular, Preclinical, and Clinical Endocrinology

Glucocorticoid receptor biology in lobular breast cancer

Candace Frerich, PhD, 2021 AACR-Lobular Breast Cancer Alliance Invasive Lobular Carcinoma Research Fellow

Biomarkers Predictive of Therapeutic Benefit 3

Characterizing the molecular underpinnings of sorafenib sensitivity in desmoid tumors

James L. Chen, MD, 2020 AACR-Bayer Innovation and Discovery Grant recipient

Drug Resistance and Reversal of Resistance

Tumor treating fields suppression of ciliogenesis enhances temozolomide toxicity

Matthew R. Sarkisian, PhD 2019 AACR-Novocure Tumor Treating Fields Research Grant recipient

Preclinical Radiotherapeutics

Tumor Treating Fields in combination with radiation cause significant delay in tumor growth in in-vivo mice models

Debabrata Saha, PhD. 2020 AACR-Novocure Tumor Treating Fields Research Grant recipient

Tyrosine Kinase and Phosphatase Inhibitors

Effective multitargeted kinase inhibitors for metastatic castration-resistant prostate cancer predicted by integrative systems-based modeling

Eleonora Dondosolla, PhD. 2019 AACR-Bayer Innovation and Discovery Grant recipient

Online posters (not presented in-person)

DNA Damage and Repair

RNA-mediated DNA repair: A novel repair pathway in homologous recombination-deficient cancers

Manisha Jalan, DPhil. 2020 AACR-Swim Across America Cancer Research Fellow

Small Molecule Therapeutic Agents

A characterisation of direct and indirect transcription factor inhibition to target brachyury in chordoma

Hadley E. Sheppard, PhD. 2019 AACR-Cancer Research UK Transatlantic Fellow