AACR Project GENIE: Frequently Asked Questions
If the answer to your question is not found here or in the data guide, contact us. Q. I...
AACR Project GENIE® at the AACR Annual Meeting 2025
The AACR Annual Meeting is the touchstone of the cancer research community, the place where scientists, clinicians, other health...
AACR Project GENIE®: Powering Precision Medicine
Precision medicine requires an end-to-end learning health care system, wherein the treatment decisions for patients are informed by the...
New AACR Project GENIE Paper Alert: Genomic Landscapes and Hallmarks of Mutant RAS in Human Cancers
Over the past four years, a multi-disciplinary team brought together by AACR Project GENIE from Johns Hopkins Kimmel Cancer...
AACR Project GENIE®: Data
The first AACR Project GENIE public data release was available to the global community in January 2017; our current...
AACR Project GENIE: Biopharma Collaborative
In 2019, AACR Project Genomics Evidence Neoplasia Information Exchange (GENIE) launched a five-year research collaboration, The Biopharma Collaborative (BPC),...
AACR Project GENIE®: Governance
AACR Project GENIE® is governed by a steering committee comprised of one representative from each participating institution, one of...
11 Most Common Cancer Types in the AACR Project GENIE® Registry
Select a cancer type listed below to view summary statistics for point mutations, gene fusions, and copy number alterations...
AACR Project GENIE®: Participation
Participation Map PARTICIPATING INSTITUTIONS: North America Participating Institutions: Europe and the United Kingdom Participating Institutions: Asia Participating Institution Requirements...
News and Updates
AACR Project GENIE 19.0-Public Release LATEST News
Featured Cancers
Lung cancer Pancreatic Cancer breast cancer hepatobiliary cancer Appendiceal cancer sarcoma and bone cancer Prostate melanoma Kidney Cancer Colorectal...
Year In Review | 2025
By the numbers There have been two additional public data releases, now totaling 18. The latest consortium release contains...
BPC NSCLC V2.0-public
The GENIE BPC NSCLC v2.0-public dataset contains 1,846 NSCLC patients from four institutions: MSKCC, DFCI, VICC and UHN. Data...
Collaborate
AACR Project GENIE® functions as a nonprofit, contract research organization (CRO) wholly owned by the American Association for Cancer...
Landmarks in Cancer Research: 2011-Present
2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 References
BPC CRC v2.0-public
The GENIE BPC CRC v2.0-public dataset contains 1,485 CRC patients from three institutions: MSKCC, DFCI, and VICC. Data Access: ...
Non-Small Cell Lung Cancer
Figure 1: The most commonly mutated genes in non-small cell lung cancer (NSCLC) in the AACR Project GENIE® registry...
Colorectal Cancer
The most commonly mutated genes in colorectal cancer in the AACR Project GENIE® registry in release 12.0-public. Inset displays the...
Pancreatic Cancer
Figure 1: The most commonly mutated genes in pancreatic cancer in the AACR Project GENIE® registry in release 12.0-public. Inset...
AACR Timeline—At the Forefront of Cancer Science in the 21st Century: 2000-Present
2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018...
Early-onset BrCa
BPC BrCA V1.0-public See an overview of the data set. What is included in GENIE BPC data?
Glioma
Figure 1: The most commonly mutated genes in glioma in the AACR Project GENIE® Registry in release 12.0-public Figure...
Leukemia
Figure 1: The most commonly mutated genes in Leukemia in the AACR Project GENIE® registry in release 12.0-public. Figure...
BPC Core Team 2025
Shawn M. Sweeney, American Association for Cancer Research: Project GENIE Tony Wu, American Association for Cancer Research: Project GENIE...
Cancer of Unknown Primary
Figure 1: The most commonly mutated genes in cancer of unknown primary in the AACR Project GENIE® Registry in...
Ovarian Cancer
Figure 1: The most commonly mutated genes in ovarian cancer in the AACR Project GENIE® Registry in release 12.0-public...
Registry
The GENIE Registry is a continuously evolving, publicly available real-world data resource, housing: 230,000+ clinical-grade genomic samples from 200,000+...
Breast Cancer
Figure 1: The most commonly mutated genes in the BRCA AACR Project GENIE® registry in release 12.0-public. Figure 2:...
Mature B-Cell Cancer
Figure 1: The most commonly mutated genes in Mature B-Cell Neoplasms in the AACR Project GENIE® Registry in release...