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AACR-Novocure Career Development Awards for Tumor Treating Fields Research | Grant Status - Open

Grant Amount$ 225,000 USD

Grant Term

3 Year(s)

Start of Grant Term

7/1/2020

Application Deadline

12/11/2019 1:00:00 PM

Decision Date

2/2020

Additional Information

​April 28, 2020 – Grant recipients must attend the Grants Reception and Dinner to formally accept the grant. Grant funds may be used to support the grantee's registration and attendance at this Annual Meeting.

Description

The AACR-Novocure Career Development Awards for Tumor Treating Fields Research represent a joint effort to promote and support early-career investigators who are conducting innovative research focused on Tumor Treating Fields (TTFields; intermediate frequency, low intensity, alternating electric fields that disrupt cell division in cancer cells). These grants are intended to provide a deeper understanding of the mechanisms of action of this novel anti-cancer treatment modality and to accelerate the development of new treatment strategies to advance therapeutic options for cancer. The research proposed for funding should be basic or translational in nature, promoting the transition of in vitro work into in vivo systems. Likewise, proposals focused on 1) translational approaches, promoting the transition of in vitro work into in vivo systems, 2) combination therapies involving TTFields, or 3) bringing treatments involving TTFields to the clinic, are strongly encouraged.

Applications are invited from researchers affiliated with institutions* that currently hold a Materials Transfer Agreement (MTA) with Novocure for use of its devices (*Please see Table 1 for a list of institutions on page 18 of the Program Guidelines).

In addition, applications are invited from researchers that have not yet entered into a Materials Transfer Agreement (MTA) with Novocure. If selected for funding, Novocure will work with the institution to execute a MTA to provide the necessary devices to complete the research. For additional details, please see the Materials Transfer Agreement and Terms and Conditions.

Each award provides a three-year grant of $225,000 for expenses related to the research project, which may include salary and benefits of the grant recipient and any collaborators*, postdoctoral or clinical research fellows, graduate students (including tuition costs associated with graduate students' education and training), or research assistants; research/laboratory supplies; equipment; publication charges for manuscripts that pertain directly to the funded project; and other research expenses. (*Note that inter-laboratory collaboration is encouraged.)

Program Guidelines

Research Project Criteria

Research projects should examine the use of TTFields as a therapeutic modality. The research proposed for funding should be basic or translational in nature, promoting the transition of in vitro work into in vivo systems. Likewise, proposals focused on 1) translational approaches, promoting the transition of in vitro work into in vivo systems, 2) combination therapies involving TTFields, or 3) bringing treatments involving TTFields to the clinic, are strongly encouraged.

Research proposals must incorporate use of the Inovitro® system into the experimental design. For grant recipients who are affiliated with institutions that do not currently hold a Materials Transfer Agreement (MTA) with Novocure for use of its devices, Novocure will provide this system to complete the research. For additional details, please see the MTA and Terms and Conditions. If selected for funding, Novocure will work with the institution to execute a MTA.

Eligibility Criteria

​Applicants must have a doctoral degree (PhD, MD, MD/PhD, or equivalent) in a related field and not currently be a candidate for a further doctoral degree.

At the start of the grant term on July 1, 2020, applicants must hold a faculty position with the title of assistant professor, instructor, research assistant professor, or the equivalent; have completed their most recent doctoral degree within the past 11 years (i.e., degree cannot have been conferred before July 1, 2009); have independent laboratory space as confirmed by their institution; and work at an academic, medical, or research institution anywhere in the world.

Investigators may submit only one application for the AACR-Novocure Career Development Awards for Tumor Treating Fields Research but may concurrently apply for other AACR grants. However, applicants are expected to accept the first grant they are awarded. Individuals may accept and hold only one AACR grant at a time.

Employees or subcontractors of a U.S. government entity or for-profit private industry are not eligible. Employees or subcontractors of a U.S. government entity or for‐profit private industry may serve as Collaborators, but no grant funds may be directed towards these individuals.

Investigators who are currently, or have been, a Principal Investigator on a substantial independent research award (e.g., an NIH R01 award, DP2 award, DP5 award, MIRA award, or the equivalent) are not eligible. Qualified investigators are invited to apply for AACR grants for independent investigators.

Postdoctoral or clinical research fellows or the equivalent who are working under the auspices of a scientific mentor are not eligible to apply. Qualified fellows are invited to apply for an AACR Fellowship.

Any individual who currently holds an active AACR grant may not apply. Past AACR grantees may apply if they complied with all progress and financial report requirements.  

All applicants with questions about eligibility should contact the AACR's Scientific Review and Grants Administration at grants@aacr.org before submitting an application.

Citizenship Requirements

​There are no citizenship or geographic requirements. However, by submitting an application for this grant, an applicant applying from an institution located in a country in which they are not a citizen or a permanent resident assures that the visa status will provide sufficient time to complete the project and grant term at the institution from which they applied.

AACR Membership Requirements

Applicants should be AACR members. Nonmembers interested in this grant opportunity must submit a satisfactory application for AACR Active membership, and be members in good standing, by the grant application deadline. Nonmembers can apply for membership using the Official Application for Membership submitted to the AACR with the required documents or apply online. Suspended Members can renew their membership through their myAACR account. Lapsed members should contact the Membership Department at membership@aacr.org for assistance and with any questions.

Application Instructions

​The AACR requires applicants to submit an online application by 1:00 p.m. U.S. Eastern Time on Wednesday, December 11, 2019, using the proposalCENTRAL website at https://proposalcentral.com.

Program Guidelines and Application Instructions are available in PDF format.