Infection With Dengue Virus May Increase the Risk of Leukemia
PHILADELPHIA – Compared with individuals without a history of dengue virus infection, those previously infected with the virus had...
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Peripheral Blood From Patients with Metastatic Solid Tumors Is A Source of p53-reactive T cells
PHILADELPHIA — T cells targeting p53 hotspot mutations can be harvested from peripheral blood of patients with metastatic solid epithelial cancers, according to...
Targeted Therapy Combination Shows Promising Antitumor Activity in Aggressive Meningiomas
PHILADELPHIA — The targeted therapy combination of the mTOR inhibitor everolimus (Afinitor) and the somatostatin agonist octreotide (Sandostatin) yielded...
Adolescent and Young Adult Cancer Survivors May Have an Elevated Risk of Hospitalizations
PHILADELPHIA — Adolescent and young adults who survived at least two years after a cancer diagnosis had nearly double...
New AACR Journal, Blood Cancer Discovery, Publishes Its First Paper
Study reports the landscape of mutations present in pediatric acute lymphoblastic leukemia (ALL) and how this landscape changes during...
American Cancer Survivors Face Substantial Financial Hardship and Financial Sacrifices
PHILADELPHIA —American cancer survivors, particularly those 64 years or younger, faced substantial medical financial hardship and sacrifices in spending,...
Circulating Tumor DNA May Be Predictive of Disease Progression in Patients with Rectal Cancer
PHILADELPHIA — Detection of circulating tumor DNA (ctDNA) after neoadjuvant chemoradiotherapy was associated with poor response and increased risk...
BRAF Inhibitor Shows Promising Results in Pediatric Patients with Low-Grade Glioma
PHILADELPHIA — Dabrafenib (Tafinlar), a BRAF inhibitor approved to treat certain types of adult melanoma, showed activity in pediatric...
Anti-CTLA-4 Antibody Tremelimumab Shows Efficacy in Patients With Metastatic Bladder Cancer
PHILADELPHIA — Treatment with the investigational anti-CTLA-4 agent tremelimumab showed clinical responses in patients with pretreated metastatic bladder cancer,...
Commercial Prognostic Tests for Prostate Cancer May Not Be Accurate in African American Men
PHILADELPHIA — Commercial gene expression tests that guide treatment decisions for prostate cancer may not accurately predict risk of...