Fixed-duration Ibrutinib Plus Venetoclax May Benefit Patients with High-risk Chronic Lymphocytic Leukemia
PHILADELPHIA – First-line ibrutinib (Imbruvica) plus venetoclax (Venclexta) led to high response and survival rates in patients with chronic...
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Pancreatic Lesions May Occur More Frequently Than Previously Thought
Researchers partnered with Gift of Life Michigan to analyze healthy pancreata from deceased donors PHILADELPHIA – Pancreatic intraepithelial neoplasia...
AACR Names New Editor-in-Chief of the Journal Cancer Research
PHILADELPHIA – The American Association for Cancer Research (AACR) today announced the appointment of Christine A. Iacobuzio-Donahue, MD, PhD,...
New Treatment Regimen May Decrease Mortality in Patients With Cardiotoxicity From Immune Checkpoint Inhibitors
Treatment consisted of high-dose abatacept, ruxolitinib, and proactive monitoring for respiratory muscle involvement PHILADELPHIA – Among cancer patients who...
Neoadjuvant Nivolumab Shows Long-term Benefit in Patients with Non-small Cell Lung Cancer
Study reports five-year survival outcomes PHILADELPHIA – Patients with resectable non-small cell lung cancer (NSCLC) who were treated with...
Clonal Hematopoiesis May Be More Common Among Pediatric Cancer Survivors Than the General Population
Researchers identified mutational signatures characteristic of chemotherapy exposure PHILADELPHIA – Researchers identified a higher rate of clonal hematopoiesis (CH)...
An Investigational T-cell Therapy Shows Promise Against Six Viral Infections Common After Stem Cell Transplants
Responses to the off-the-shelf therapy were observed in 95 percent of patients PHILADELPHIA – Posoleucel, an investigational allogeneic off-the-shelf...
Few Americans are Aware of Links Between Alcohol and Cancer Risk
Awareness varied between wine, beer, and liquor PHILADELPHIA – Despite conclusive research that shows that all alcoholic beverages, including...
Low Blood Phosphate Levels May Be Linked to Neurological Side Effects From CAR T-cell Therapy
PHILADELPHIA – Incidence and severity of neurological side effects from chimeric antigen receptor (CAR) T-cell therapy were higher in...
Specific Components of the Tumor Immune Microenvironment May Affect the Durability of Responses to BCMA CAR T-cell Therapy
Results suggest that immune cells beyond CAR-T cells impact the efficacy of CAR T-cell therapy PHILADELPHIA – Patients with...