Whole-body Screening and Education in Melanoma-prone Families May Improve Early Detection of Disease
PHILADELPHIA – Among patients at high risk of melanoma, those who received routine skin cancer screening and education about...
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Mutations in Circulating Tumor Cells May Predict Clinical Outcomes in Patients with Metastatic Castrate-resistant Prostate Cancer
PHILADELPHIA – Various genetic alterations in circulating tumor cells (CTCs) were associated with clinical outcomes and resistance to hormone...
Ambulatory Function Among Cancer Survivors May be an Important Determinant for Survival
PHILADELPHIA – Cancer survivors had a greater risk of reduced ambulatory function, which was associated with an increased risk...
Machine Learning Tool Can Predict Malignancy in Patients With Multiple Pulmonary Nodules
PHILADELPHIA – A machine learning-based tool was able to predict the risk of malignancy among patients presenting with multiple...
Native American Ancestry Associated With Increased Mutations in EGFR Gene Among Latin American Patients With Lung Cancer
PHILADELPHIA – Among patients with lung cancer from Latin America, genomic and ancestry analyses revealed that Native American ancestry...
Use of Dexamethasone May Decrease the Efficacy of Immune Checkpoint Inhibitors in Patients With Glioblastoma
PHILADELPHIA – Among patients with glioblastoma receiving an immune checkpoint inhibitor, those who received the corticosteroid dexamethasone at baseline...
Artificial Intelligence May Help Predict Response to Immune Checkpoint Blockade in Patients With Metastatic Melanoma
PHILADELPHIA – A computational method that combines clinicodemographic variables with deep learning of pre-treatment histology images could predict response...
Cancer Deaths Resulted in More Than 4 Million Potential Years of Life Lost in 2017
PHILADELPHIA – Deaths from cancer accounted for more than 4 million potential years of life lost in 2017, according...
The Lung Microbiome May Affect Lung Cancer Pathogenesis and Prognosis
PHILADELPHIA – Enrichment of the lungs with oral commensal microbes was associated with advanced stage disease, worse prognosis, and...
Genetic Alterations May Contribute to Greater Prostate Cancer Incidence and Mortality Among African American Men
PHILADELPHIA – Prostate cancer tumors from African American men had higher frequencies of certain genetic alterations that may be...