Bispecific CAR T-cell Therapy Shows Early Promise for Relapsed or Refractory B-cell Lymphoma
PHILADELPHIA – Bispecific anti-CD19/CD20 chimeric antigen receptor (CAR) T-cell therapy was well tolerated and showed signs of clinical efficacy...
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Oncolytic Herpesvirus Shows Early Promise in Pediatric Patients with High-grade Glioma
PHILADELPHIA – Treatment with a modified herpesvirus in combination with radiation therapy was well tolerated and showed signs of...
Neoadjuvant Nivolumab plus Chemotherapy Increased Pathological Complete Response Rate in CheckMate-816 Lung Cancer Trial
PHILADELPHIA – Adding nivolumab (Opdivo) to chemotherapy as neoadjuvant treatment for patients with resectable non-small cell lung cancer (NSCLC)...
Rare Pathogenic Germline Variants Were Observed in Sporadic Pediatric Neuroblastoma Cases and Were Inherited
PHILADELPHIA – Pediatric patients with sporadic neuroblastoma harbored rare pathogenic variants in cancer predisposition genes that were inherited and...
Cancer Aneuploidy May Predict Responses to Immunotherapy in Patients with Non-small Cell Lung Cancer
PHILADELPHIA – Lower levels of cancer aneuploidy were associated with more favorable outcomes after immune checkpoint inhibition in patients...
AACR Announces Fellows of the AACR Academy Class of 2021
PHILADELPHIA – The American Association for Cancer Research (AACR) today announced its newly elected class of Fellows of the...
Patients Receiving Chemotherapy May Not be at Increased Risk for COVID-19
Study shows disruptions to cancer treatment could be minimized during the pandemic PHILADELPHIA – Compared with patients with cancer...
Patients With Lymphoma Treated With B-cell-depleting Therapies May Have Worse Outcomes From COVID-19 Infection
PHILADELPHIA – Among patients with lymphoma admitted to the hospital for severe COVID-19, those treated with B-cell-depleting therapies within...
Drive-by FluFIT Clinics May Increase Colorectal Cancer Screening Rates During the COVID-19 Pandemic
PHILADELPHIA – Administering colorectal cancer screening kits through a socially distant drive-by flu vaccination clinic increased access to colorectal...
Circulating Tumor Cell Dynamics May Predict Treatment Response and Prognosis in Patients with Metastatic Breast Cancer
SAN ANTONIO – Early circulating tumor cell dynamics were associated with overall survival in patients with metastatic breast cancer,...