Breast Cancer Mortality in Women Ages 20-49 Significantly Dropped Between 2010 and 2020
CHICAGO – From 2010 to 2020, breast cancer deaths among women ages 20-49 declined significantly across all breast cancer...
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Single-cell RNA Sequencing Provides Comprehensive Map of Acute Myeloid Leukemia Cell States
Study establishes a reference for normal hematopoietic cell differentiation and identifies novel acute myeloid leukemia cell states with potential...
American Association for Cancer Research Inaugurates New Leadership During AACR Annual Meeting 2025
Lillian L. Siu, MD, FAACR, begins term as AACR President CHICAGO – The members of the American Association for...
Oral HER2-targeted Therapy Zongertinib Demonstrates Clinical Benefit in Advanced HER2-mutated Lung Cancer
CHICAGO – Zongertinib, a human epidermal growth factor receptor 2 (HER2)-targeted tyrosine kinase inhibitor, elicited durable responses in patients...
A Liquid Biopsy-based Assay Could Detect Recurrence Prior to Imaging in Patients With Resectable Colorectal Cancer
CHICAGO – An ultrasensitive circulating tumor DNA (ctDNA)-based liquid biopsy assay detected signs of recurrence prior to imaging and...
AI-driven Analysis of Digital Pathology Images May Improve Pediatric Sarcoma Subtyping
CHICAGO – An artificial intelligence (AI)-based model accurately classified pediatric sarcomas using digital pathology images alone, according to results...
A Topical BRAF-inhibiting Gel May Mitigate Acneiform Rash in Patients Receiving EGFR-targeted Therapy for Colorectal Cancer
CHICAGO – Patients with colorectal cancer who had acneiform rash and applied LUT014 gel, an investigational topical BRAF inhibitor,...
AI-driven Biomarker Model May Improve Detection of Cancer Cachexia
CHICAGO – A multimodal, artificial intelligence (AI)-driven model that analyzes routinely collected imaging and clinical information led to more...
Pretrained Machine Learning Models May Help Accurately Diagnose Nonmelanoma Skin Cancer in Resource-limited Settings
CHICAGO – Artificial intelligence models, pretrained on vast datasets, significantly outperformed a standard baseline model in identifying nonmelanoma skin...
Off-the-shelf CAR Natural Killer Cell Therapy with Logic Gates Elicits Complete Remissions in Relapsed or Refractory Blood Cancers
CHICAGO – Several patients with acute myeloid leukemia (AML), who were treated with SENTI-202, a first-in-class chimeric antigen receptor...