CDK4/6 Inhibitors Effective in Mice Bearing Multiple Human Cancer Types
BOSTON – Cyclin-dependent kinase (CDK) inhibitors, including palbociclib, were effective against patient-derived xenograft (PDX) mouse models of different tumor...
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Bispecific Antibody MCLA-128 Shows Clinical Activity in Patients With Solid Tumors Harboring NRG1 Gene Fusions
BOSTON – The investigational bispecific HER2/HER3 antibody therapeutic MCLA-128 showed radiological and clinical responses in patients with metastatic pancreatic...
AG-270 is Safe and Shows Signs of Activity in Patients with Cancers Lacking the MTAP Gene
BOSTON – The investigational therapeutic AG-270, which targets the protein MAT2A, was safe, tolerable, and showed signs of activity...
Colorectal Cancer Mortality and Racial Disparity Varies Across U.S. Cities
SAN FRANCISCO – Racial disparities in death rates from colorectal cancer vary considerably across cities in the United States,...
Second Opinions from Comprehensive Cancer Centers Changed Treatment Plans for African American Patients
Study examined feasibility, potential benefits of collaboration SAN FRANCISCO – African American breast cancer patients who received second opinions...
Disparities in Toxic Heavy Metal Exposures Correlated With Increased Risk of Breast Cancer Among Minority Populations in Chicago
SAN FRANCISCO – Among women in Chicago, African Americans and Hispanics were exposed to higher levels of ambient toxic...
Survey Suggests LGBTQI+ Latinx Community Not Receiving Tailored Cancer-related Information and Health Care
SAN FRANCISCO – Most LGBTQI+ Latinx have been afraid to share their gender identity and/or sexual orientation with a...
Poor and Minority Patients are More Likely to Have Cancer Detected via Emergency Room Visit
SAN FRANCISCO – Medicare patients from lower socioeconomic groups and several ethnic minority groups were more likely than their...
Culturally Tailored Intervention Enabled Low-income Asian American Women to Conduct HPV Self-sampling Test
SAN FRANCISCO – A culturally tailored intervention to improve human papillomavirus (HPV) screening among low-income Asian American women significantly...
Immune Cell Therapy Shows Early Promise for Patients With Pancreatic Cancer
SAN FRANCISCO – A nonengineered, multiantigen-specific T-cell therapy was safe, tolerable, and showed signs of clinical activity in patients...