HER2-targeted CAR T-cell Therapy Safe, With Promising Antitumor Activity in Patients With Advanced Sarcoma
ATLANTA – A combination of chemotherapy and chimeric antigen receptor (CAR) T cells designed to target the protein HER2...
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Immune Checkpoint Inhibitor Combination Efficacious For Patients With High-grade Neuroendocrine Carcinoma
ATLANTA – A combination of the anti-CTLA-4 immunotherapeutic ipilimumab (Yervoy) and the anti-PD-1 immunotherapeutic nivolumab (Opdivo) showed clinical benefit...
Adding the MET Inhibitor Savolitinib to Osimertinib was Beneficial for Certain Pretreated Lung Cancer Patients in TATTON Trial
ATLANTA – Adding the investigational MET inhibitor savolitinib to the EGFR inhibitor osimertinib (Tagrisso) yielded clinical responses in patients...
Liquid Biopsy-based Test As Good As Tissue-based Test for Identifying Treatment for Lung Cancer
Single test could identify one prognostic and seven predictive biomarkers in blood PHILADELPHIA – Guardant360, a liquid biopsy test...
Prostate Cancer Patients With Cardiovascular Disease Had Higher Mortality After Starting Abiraterone Acetate
Clinical trial data may not be generalizable to real-world population PHILADELPHIA – Patients with advanced prostate cancer who had...
Dietary Factors Affecting Gut Microbiome May Influence Response to Immunotherapy in Melanoma Patients
PHILADELPHIA – Among melanoma patients treated with anti-PD-1 immunotherapy, consumption of a high-fiber diet was associated with higher gut...
Survey of Young-onset Colorectal Cancer Patients Suggests Misdiagnosis May Be Common
PHILADELPHIA – Many patients diagnosed with colorectal cancer before age 50 were initially misdiagnosed, which may lead to diagnosis...
AACR to Host 2019 Annual Meeting in Atlanta, March 29-April 3
The American Association for Cancer Research (AACR) will be hosting its 110th Annual Meeting, March 29-April 3, 2019, at...
Lifestyle Intervention Helped Breast Cancer Survivors Lose Weight, and Was Associated with Higher Disease-free Survival Rates
SAN ANTONIO – Survivors of early-stage breast cancer who participated in a lifestyle intervention on healthy habits lost weight...
Oxybutynin Decreased Frequency of Hot Flashes, Improved Quality of Life for Breast Cancer Survivors
SAN ANTONIO – Treatment with oxybutynin helped reduce the frequency and intensity of hot flashes for women who could...