HER2-targeted CAR T-cell Therapy Safe, With Promising Antitumor Activity in Patients With Advanced Sarcoma
ATLANTA – A combination of chemotherapy and chimeric antigen receptor (CAR) T cells designed to target the protein HER2...
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Immune Checkpoint Inhibitor Combination Efficacious For Patients With High-grade Neuroendocrine Carcinoma
ATLANTA – A combination of the anti-CTLA-4 immunotherapeutic ipilimumab (Yervoy) and the anti-PD-1 immunotherapeutic nivolumab (Opdivo) showed clinical benefit...
Adding the MET Inhibitor Savolitinib to Osimertinib was Beneficial for Certain Pretreated Lung Cancer Patients in TATTON Trial
ATLANTA – Adding the investigational MET inhibitor savolitinib to the EGFR inhibitor osimertinib (Tagrisso) yielded clinical responses in patients...
Prostate Cancer Patients With Cardiovascular Disease Had Higher Mortality After Starting Abiraterone Acetate
Clinical trial data may not be generalizable to real-world population PHILADELPHIA – Patients with advanced prostate cancer who had...
Dietary Factors Affecting Gut Microbiome May Influence Response to Immunotherapy in Melanoma Patients
PHILADELPHIA – Among melanoma patients treated with anti-PD-1 immunotherapy, consumption of a high-fiber diet was associated with higher gut...
Survey of Young-onset Colorectal Cancer Patients Suggests Misdiagnosis May Be Common
PHILADELPHIA – Many patients diagnosed with colorectal cancer before age 50 were initially misdiagnosed, which may lead to diagnosis...
Liquid Biopsy-based Test As Good As Tissue-based Test for Identifying Treatment for Lung Cancer
Single test could identify one prognostic and seven predictive biomarkers in blood PHILADELPHIA – Guardant360, a liquid biopsy test...
AACR to Host 2019 Annual Meeting in Atlanta, March 29-April 3
The American Association for Cancer Research (AACR) will be hosting its 110th Annual Meeting, March 29-April 3, 2019, at...
Exercise Performed During Adjuvant Breast Cancer Treatment May Improve Cardiovascular Function
SAN ANTONIO – Women who underwent a supervised program of cardiovascular exercise during adjuvant breast cancer treatment experienced better...
Lifestyle Intervention Helped Breast Cancer Survivors Lose Weight, and Was Associated with Higher Disease-free Survival Rates
SAN ANTONIO – Survivors of early-stage breast cancer who participated in a lifestyle intervention on healthy habits lost weight...