MRTX849 Shows Clinical Activity in Patients With KRAS G12C-mutant Solid Cancers
BOSTON The investigational KRAS G12C inhibitor MRTX849 yielded clinical responses in patients with non-small cell lung cancer (NSCLC) and...
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Selumetinib Shows Clinical Benefit in Adult Patients with Neurofibromatosis Type 1-Associated Plexiform Neurofibromas
BOSTON – The investigational MEK inhibitor selumetinib showed clinical responses in adult patients with neurofibromatosis type 1-associated plexiform neurofibromas,...
CDK4/6 Inhibitors Effective in Mice Bearing Multiple Human Cancer Types
BOSTON – Cyclin-dependent kinase (CDK) inhibitors, including palbociclib, were effective against patient-derived xenograft (PDX) mouse models of different tumor...
Bispecific Antibody MCLA-128 Shows Clinical Activity in Patients With Solid Tumors Harboring NRG1 Gene Fusions
BOSTON – The investigational bispecific HER2/HER3 antibody therapeutic MCLA-128 showed radiological and clinical responses in patients with metastatic pancreatic...
AG-270 is Safe and Shows Signs of Activity in Patients with Cancers Lacking the MTAP Gene
BOSTON – The investigational therapeutic AG-270, which targets the protein MAT2A, was safe, tolerable, and showed signs of activity...
AACR Congratulates Newest Members of the National Academy of Medicine
Among those recognized are 19 members of the AACR PHILADELPHIA – The American Association for Cancer Research (AACR) congratulates...
Call for Entries: 2020 AACR June L. Biedler Prize for Cancer Journalism
Submission deadline is November 12 PHILADELPHIA – The American Association for Cancer Research (AACR) announces the call for entries...
Monoclonal Antibody Treatment Combined with Induction Chemotherapy Yielded Promising Outcomes in High-Risk Neuroblastoma
PHILADELPHIA – Combining an investigational anti-GD2 monoclonal antibody with induction chemotherapy yielded promising two-year event-free survival in pediatric patients...
AACR Congratulates Dr. William G. Kaelin Jr., Sir Peter J. Ratcliffe, and Dr. Gregg L. Semenza on 2019 Nobel Prize in Physiology or Medicine
PHILADELPHIA – The American Association for Cancer Research (AACR) congratulates Fellow of the AACR Academy William G. Kaelin Jr.,...
Cancer Incidence and Most Common Types Vary Among American Indians and Alaska Natives
Rates show significant variation by geographic regions for these groups than for whites PHILADELPHIA: The nation’s American Indian and...