Program: Thursday, July 23
Please note that this meeting will take place as an in-person event in Boston, Massachusetts and will not live-stream content for virtual participation. The meeting content will be recorded and made available as an on-demand program after the conference.
All presentations are scheduled to be live, in-person presentations at the date and time specified below unless noted otherwise. Program in progress.
*-Short talk from proffered abstract
Thursday, July 23
- Networking Breakfast
- Keynote Lecture
- Plenary Sessions 3-4
- Plenary Session 3: AI in Oncology: Facts and Hopes
- Plenary Session 4: Super CARs – Future of CAR-T Cell Therapy
- Concurrent Roundtables 1-2
- Roundtable 1: Policy
- Roundtable 2: Accelerating Investigator-Initiated Clinical Trials with Team Science
- Novel Therapeutics: Biotech Spotlight Session 1
- Drugging the Surfacesome Sessions 1-3
- Drugging the Undruggable Session 1: Drug Conjugates for Solid Tumors – Choosing the Right Modality for the Right Target
- Drugging the Undruggable Session 2: Multispecifics
- Drugging the Undruggable Session 3: Radionucleotides
- Poster Session B
Networking Breakfast
7-8 am | Independence Ballroom West
Keynote Lecture
8-9 am | Grand Ballroom
- 8:05 a.m. | Keynote Lecture
William R. Sellers, Broad Institute of MIT and Harvard, Cambridge, Massachusetts - 8:45 a.m. | Q&A
Break
9-9:15 a.m. | Grand Ballroom Prefunction
Plenary Sessions 3-4
9:15-11:15 a.m.
Plenary Session 3: AI in Oncology: Facts and Hopes
Grand Ballroom
Session Chair: Sarah Skerratt, Chief Research Officer, Isomorphic Labs, London, United Kingdom
- 9:20 a.m. | Sarah Skerratt
- 9:50 a.m. | Jorge Reis-Filho, AstraZeneca, New York, New York
- 10:20 a.m. | Benjamin Haibe-Kains, UHN Princess Margaret Cancer Centre, Toronto, Ontario, Canada
- 10:50 a.m. | Panel Discussion
Plenary Session 4: Super CARs – Future of CAR-T Cell Therapy
Constitution Ballroom A
Session Chair: Saar I. Gill, University of Pennsylvania, Philadelphia, Pennsylvania
- 11:05 a.m. | In vivo CAR-T
Saar I. Gill - 11:35 a.m. | Speaker to be announced
- 12:05 p.m. | Armored CAR-T
Alexandra M. Haugh, Massachusetts General Hospital, Boston, Massachusetts - 12:35 p.m. | Panel Discussion
Break
11:15-11:30 a.m.
Concurrent Roundtables 1-2
11:30 a.m.-12:30 p.m.
Roundtable 1: Policy
Constitution Ballroom A
- 11:30 a.m. | Introductions
- 11:40 a.m. | Discussion
- 12:15 p.m. | Q&A
Roundtable 2: Accelerating Investigator-Initiated Clinical Trials with Team Science
Constitution Ballroom B
Moderator: Elizabeth A. Jaffee, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland
- 11:30 a.m. | Introductions
- 11:40 a.m. | Discussion
Panelists:
Jayesh Desai, Peter MacCallum Cancer Centre, Melbourne, Australia
Sarah Goldberg, Yale University, New Haven, Connecticut
Matthew D. Hellmann, AstraZeneca, Gaithersburg, Maryland
Anthony Joshua, Garvan Institute of Medical Research, Sydney, NSW, Australia
Anirban Maitra, NYU Langone Health Perlmutter Cancer Center, New York, New York - 12:15 p.m. | Q&A
Lunch on Own
12:30-2:45 p.m.
Novel Therapeutics: Biotech Spotlight Session 1
3-4:30 p.m. | Grand Ballroom
Moderators: Christiana Bardon, MPM BioImpact, Boston, Massachusetts, Michael A. Caligiuri, City of Hope National Medical Center, Duarte, California, and William N. Hait, Johnson & Johnson (ret.), New Brunswick, New Jersey
Break
4:30-4:45 p.m. | Grand Ballroom Prefunction
Drugging the Surfacesome Sessions 1-3
4:45-6:15 p.m.
Drugging the Surfacesome 1: Drug conjugates for solid tumors – Choosing the Right Modality for the Right Target
Grand Ballroom
Session Chair: Raffaele Colombo, Zymeworks Inc., Vancouver, British Columbia, Canada
- 4:50 p.m. | Advancements in small molecule drug conjugates with cytotoxic payloads and radioligands
Dario Neri, ETH Zurich, Zurich, Switzerland - 5:10 p.m. | Radioconjugated antibodies and antibody fragments as precision therapeutics
Andrew M. Scott, Olivia Newton-John Cancer Research Institute, Heidelberg, VIC, Australia - 5:30 p.m. | Optimizing payload delivery: Lessons from ADC mechanisms and clinical translation
Jamie Rich, Zymeworks Inc., Vancouver, British Columbia, Canada - 5:50 p.m. | Molecular imaging in drug development and as a biomarker to guide treatment decisions: What we learn from imaging antibody-based agentsin patients
Elisabeth De Vries, University Medical Center Groningen, Groningen, The Netherlands
Drugging the Surfacesome 2: Multispecifics
Constitution Ballroom A
Session Chair: Daniel S. Chen, Synthetic Design Lab, San Carlos, California
- 4:50 p.m. | Multispecific protein expression and proximity therapeutics
Pamela Holland, InduPro, Seattle, Washington - 5:10 p.m. | Multifunctional multivalent multispecific therapeutics
Daniel S. Chen - 5:30 p.m. | Djuro Karanovic, AstraZeneca, Gaithersburg, Maryland
- 5:50 p.m. | Panel Discussion
Drugging the Surfacesome 3: Radionucleotides
Constitution Ballroom B
Session Chair: H. Charles Manning, The University of Texas MD Anderson Cancer Center, Houston, Texas
- 4:50 p.m. | Speaker to be announced
- 5:10 p.m. | Speaker to be announced
- 5:30 p.m. | Carolyn J. Anderson, University of Missouri, Columbia, Missouri
- 5:50 p.m. | Panel Discussion
Poster Session B / Reception
6:15-8:45 p.m. | Back Bay Ballroom
Evening off / Dinner on own
8:45 p.m.