In This Section

Program: Wednesday, February 18

Thursday, Feb. 19 Friday, Feb 20 Saturday, Feb. 21

WEDNESDAY, FEBRUARY 18

* – Short talk selected from proffered abstracts
[R] – Remote presentation

Wednesday, February 18

REGISTRATION

12-9 p.m. | Diamond Ballroom Foyer

Educational Sessions 1-2

3-4:15 p.m.

Educational Session 1: All You Need to Know About Studying the Tumor Microenvironment

Diamond Ballroom 5-10

Session Chair: Brian Brown, Icahn School of Medicine at Mount Sinai, New York, New York

  • 3:05 p.m. | Mechanisms of tumor immune exclusion
    Brian Brown
  • 3:25 p.m. | Noninvasive profiling of the TME for immunotherapy response assessment
    Aaron M. Newman, Stanford University, Stanford, California
  • 3:45 p.m. | Discussion / Q&A

Educational Session 2: Microbiome

Diamond Ballroom 4

Session Chair: Marcel R.M. van den Brink, City of Hope, Duarte, California

  • 3:05 p.m. | Marcel R.M. van den Brink
  • 3:25 p.m. | Harnessing the microbiome for cancer immunotherapy
    Giorgio Trinchieri, National Cancer Institute, Bethesda, Maryland
  • 3:45 p.m. | Keeping your microbiome studies out of the toilet
    Michael C. Wu, Fred Hutchison Cancer Center, Seattle, Washington
  • 4:05 p.m. | Discussion / Q&A

Break

4:15-4:20 p.m. | Diamond Ballroom Foyer

Educational Sessions 3-4

4:20-5:15 p.m.

Educational Session 3: All You Need to Know About Metabolism in IO

Diamond Ballroom 5-10

Session Chair: Miguel Reina-Campos, La Jolla Institute for Immunology, La Jolla, California

  • 4:25 p.m. | Metabolic control of inflammation and aging
    Vishwa Deep Dixit, Yale Center for Research on Aging (Y-Age), Yale School of Medicine, New Haven, Connecticut [R]
  • 4:45 p.m. | T cell tissue residency and living off the land
    Miguel Reina-Campos
  • 5:05 p.m. | Discussion / Q&A

Educational Session 4: How to Artificially Design Genes and Proteins

Diamond Ballroom 4

Session Chair: Hani Goodarzi, University of California, San Francisco, California

  • 4:25 p.m. | Programming cell type-specific gene expression via AI models of chromatin accessibility
    Sebastian Castillo Hair, University of Washington, Seattle, Washington
  • 4:45 p.m. | Generative biology: Reading and writing the language of life
    Hani Goodarzi
  • 5:05 p.m. | Discussion / Q&A

Break

5:15-5:20 p.m. | Diamond Ballroom Foyer

Spotlight on Proffered Papers Session 1

5:20-6 p.m. | Diamond Ballroom 5-10

Session Chair: Christina Puig Saus, UCLA Jonsson Comprehensive Cancer Center, Los Angeles, California

  • 5:25 p.m. | Inhibition of PSGL-1 overcomes immune suppression and immunotherapy resistance in PDAC*
    Evelyn S. Sanchez Hernandez, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California
  • 5:33 p.m. | Spatial and molecular landscape in clear cell renal cell carcinoma bone metastatic patients*
    Eleonora Dondossola, The University of Texas MD Anderson Cancer Center, Houston, Texas
  • 5:41 p.m. | Using organoids and tumor infiltrating lymphocytes to elucidate the ”Dark Matter” of human tumor antigens*
    Ken-ichi Hanada, National Cancer Institute, Bethesda, Maryland
  • 5:49 p.m. | Decoding tumor microenvironment and resistance following immune checkpoint inhibition therapy in anaplastic thyroid carcinoma*
    Kartik Sehgal, Dana-Farber Cancer Institute, Boston, Massachusetts

Welcome and Keynote Session 1

6-7:30 p.m. | Diamond Ballroom 5-10

  • 6 p.m. | Welcome and Opening Keynote Lectures
    Nina Bhardwaj, Icahn School of Medicine at Mount Sinai, New York, New York
    Antoni Ribas, UCLA Jonsson Comprehensive Cancer Center, Los Angeles, California
  • 6:10 p.m. | Introduction of Keynote Speaker
    Nina Bhardwaj
  • 6:15 p.m. | Keynote
    The cancer vaccine era has arrived
    Elizabeth M. Jaffee, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland
  • 6:50 p.m. | Introduction of Keynote Speaker
    Antoni Ribas
  • 6:55 p.m. | Keynote
    Taking T cells where natural evolution hasn’t: Sustained function in the TME
    Philip D. Greenberg, Fred Hutchinson Cancer Center, Seattle, Washington

Poster Session A / Exhibit Show / Reception

7:30-10 p.m. | Platinum Ballroom