Anal Cancer

Anal cancer is a disease in which malignant cells form in the tissues of the anus, the end of the large intestine, below the rectum. The National Cancer Institute estimates that about 10,540 people in the United States will diagnosed with anal cancer in 2024, and 2,190 people will die of the disease.

The skin around the outside of the anus is called the perianal area. Tumors in this area are skin tumors, not anal cancer. Being infected with human papillomavirus (HPV) increases the risk of developing anal cancer. Other risk factors include:

  • Having many sexual partners.
  • Having receptive anal intercourse (anal sex).
  • Being older than 50.
  • Frequent anal redness, swelling, and soreness.
  • Smoking cigarettes.
Anal Cancer Prevention (PDQ®) Anal Cancer Treatment (PDQ®)

Source: National Cancer Institute